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PHARMACIST-REVIEWED GUIDE · PAKISTAN
The right painkiller, started at the right time, plus home remedies that help, and when cramps need checking.
✓ Reviewed by Arhum Nadeem, Pharm-D · ✓ Based on NHS guidance · ✓ Private WhatsApp advice
Medically reviewed by Arhum Nadeem, Pharm-D (8 years’ experience as a pharmacist) · Last reviewed: 17 October 2026
The most effective medicine for period pain for most women is an anti-inflammatory painkiller such as ibuprofen (Brufen) or mefenamic acid (Ponstan), because these reduce the prostaglandins that cause cramps. They work best when started at the first sign of pain or bleeding and taken regularly for the first day or two. Paracetamol (Panadol) is an option if you can’t take anti-inflammatories. A hot water bottle, gentle exercise and a warm bath also help. Pain that stops you from going to school or work, or that keeps getting worse, should be checked by a doctor.
Key points
| Medicine | How it helps | Notes |
|---|---|---|
| Brufen (ibuprofen) | Reduces cramp-causing prostaglandins and pain | Take with food; check the label dose |
| Ponstan Forte (mefenamic acid) 500 mg | Anti-inflammatory widely used for period pain; may also reduce heavy bleeding | Usually for the first few days of the period only; take with food |
| Synflex (naproxen) | Longer-acting anti-inflammatory | Fewer doses a day; same cautions as ibuprofen |
| Panadol (paracetamol) | Pain relief | Gentle on the stomach; a good choice if anti-inflammatories aren’t suitable |
| No-Spa (drotaverine), Buscopan Plus | Relax cramping muscle | Some women find them helpful; Buscopan Plus already contains paracetamol |
Prices change; see the product pages for current prices (October 2026). Don’t take more than the label dose, and don’t combine two anti-inflammatories. For the difference between the two main painkillers, read Paracetamol vs Ibuprofen: Which One Should You Reach For?.
During a period, the womb lining releases prostaglandins, which make the womb muscle tighten to shed its lining. Higher levels cause stronger cramps, often starting just before or when bleeding begins and lasting 1 to 3 days. This “primary” period pain is common in teenagers and young women and often eases with age or after childbirth.
“Secondary” period pain is caused by a condition such as:
If painkillers don’t control your pain, a doctor may suggest hormonal treatments such as the combined contraceptive pill, a progestogen-only option or a hormonal coil, which often make periods lighter and less painful. These need a doctor’s assessment.
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Mahwari ke dard ke liye aksar khawateen ko Brufen (ibuprofen) ya Ponstan (mefenamic acid) sab se zyada faida deti hain, kyunke yeh dard paida karne wale kemiyai mawad ko kam karti hain. Dard shuru hote hi ya khoon aate hi lein, khane ke saath, aur do dard ki goliyan ek saath na lein. Panadol bhi le sakti hain. Pait par garam bottle, garam pani se nahana aur halki walk se aaram milta hai. Agar dard itna ho ke school ya kaam par na ja sakein, ya waqt ke saath barh raha ho, to doctor ko dikhayen. Yeh endometriosis ho sakta hai.
For most women, an anti-inflammatory such as ibuprofen (Brufen) or mefenamic acid (Ponstan), started early. Paracetamol is an alternative if anti-inflammatories aren’t suitable.
Yes. Mefenamic acid (Ponstan) is commonly used for period pain and may reduce heavy bleeding too. Take it with food and don’t combine it with other anti-inflammatories.
At the first sign of cramps or when bleeding starts, then regularly at the label interval for the first day or two.
Some adults use them together within the label limits for each, because they work differently. Ask a pharmacist first if you have other health conditions.
Mild to moderate cramps are common. Pain severe enough to stop your daily life isn’t something to accept. See a doctor to check for endometriosis or fibroids.
Yes. Heat on the lower tummy relaxes the womb muscles, and studies show it can ease cramps as well as some painkillers.
This article is for general information and does not replace advice from your doctor or pharmacist. Always read the pack leaflet and follow the dose on the label or prescription.
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