Description

Description

Hydralazine HCl (20mg/ml) 1 Ampoule Injection is an antihypertensive medicine used to manage severe or emergency high blood pressure situations. It belongs to a class of drugs known as direct-acting vasodilators, and it works by relaxing the smooth muscle within blood vessel walls, particularly the arterioles. This relaxation widens the blood vessels, easing the workload on the heart and allowing blood to flow more freely, which in turn lowers blood pressure. Unlike oral antihypertensives used for everyday blood pressure control, this injectable form is generally reserved for situations where a patient cannot take medication by mouth or requires a rapid reduction in dangerously high blood pressure, such as during a hypertensive crisis or specific pregnancy-related conditions.

Ingredients

Each milliliter of Hydralazine HCl Injection contains 20mg of Hydralazine Hydrochloride as the active ingredient, along with excipients such as propylene glycol, water for injection, and pH-adjusting agents to maintain a stable, sterile solution.

Dosage Form

This medicine is supplied as a sterile, colorless injectable solution in a single-use 1ml ampoule, containing a concentration of 20mg of Hydralazine Hydrochloride per milliliter, intended for intravenous or intramuscular administration.

Uses

Hydralazine HCl Injection is primarily used to manage hypertensive emergencies, where blood pressure needs to be lowered quickly and safely under close medical supervision. It is also used to control high blood pressure in pregnant women experiencing pre-eclampsia or eclampsia, conditions where sustained high blood pressure poses risks to both mother and baby. In general, this injectable form is chosen when oral antihypertensive therapy isn’t a practical or immediate option, such as in acute care or emergency settings.

How to Use

Hydralazine HCl Injection is administered only by a doctor or trained healthcare professional, either through slow intravenous injection or intramuscular injection, and the patient’s blood pressure is typically monitored closely throughout treatment. Dosing is individualized based on the severity of the hypertensive episode and the patient’s response, and repeat doses may be given at intervals as determined by the treating physician. Once blood pressure has stabilized, patients are usually transitioned to an oral antihypertensive medication as soon as it becomes appropriate. This injection should never be self-administered.

Side Effects

Common side effects associated with Hydralazine HCl Injection include headache, loss of appetite, nausea, vomiting, and diarrhea. Some patients may also experience palpitations, a rapid heartbeat, or, in more sensitive individuals, angina-type chest discomfort. Because the medicine works by widening blood vessels, dizziness or lightheadedness can occur, especially when standing up quickly, so caution is advised around activities like driving during treatment. Less commonly, patients may experience skin flushing or digestive symptoms such as constipation. Anyone experiencing chest pain, irregular heartbeat, or signs of an allergic reaction should seek medical attention promptly.

Pregnancy & Breastfeeding

Hydralazine Injection is sometimes specifically used during pregnancy to manage severe hypertension linked to pre-eclampsia or eclampsia, but this must always be a decision made by an obstetrician or treating physician who weighs the clinical necessity against any potential risks. It is generally avoided in pregnancy unless considered essential for the mother’s and baby’s safety. Information on its transfer into breast milk is limited, so breastfeeding mothers should consult their doctor before use to determine the safest approach for their situation.

Storage Instructions

Store Hydralazine HCl ampoules at controlled room temperature, generally between 20–25°C, away from direct light and excessive heat. Keep the ampoule in its original packaging until ready for use, and store it out of the reach of children. This product is intended for single use only, and any unused solution should be discarded rather than reused. Do not use the injection if the solution appears discolored, cloudy, or contains visible particles, as this formulation can be sensitive to degradation over time.

FAQs

What is Hydralazine HCl Injection mainly used for?
It is mainly used to manage hypertensive emergencies and severe high blood pressure related to pregnancy conditions like pre-eclampsia or eclampsia.

Can this injection be given at home?
No, it must be administered by a doctor or trained healthcare professional in a clinical or hospital setting.

How quickly does Hydralazine Injection work?
When given intravenously, its effects are generally observed within a relatively short time frame, though the exact onset can vary between patients.

Is this injection safe for long-term blood pressure control?
No, it is typically used for short-term or emergency management, after which patients are usually switched to oral antihypertensive therapy.

Disclaimer

Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.