Description

Description

Spasfon (40/0.04mg) Injection is an antispasmodic medication supplied as a box of 6 ampoules, each containing 4ml of injectable solution. Its active ingredients are Phloroglucinol hydrate 40mg and Trimethylphloroglucinol 0.04mg, which work together to relax smooth muscle directly, without the anticholinergic side effects associated with some older antispasmodic medications. Spasfon is commonly used for the relief of acute spasmodic pain affecting the digestive tract, biliary system, urinary tract, and gynecological conditions. Because it acts locally on the smooth muscle itself, it is often well tolerated across a broad range of patients, including those for whom anticholinergic antispasmodics may not be suitable.

Ingredients

Each 4ml ampoule of Spasfon contains 40mg of Phloroglucinol hydrate and 0.04mg of Trimethylphloroglucinol as the active ingredients, along with pharmaceutical excipients that help maintain the stability and safety of the solution for intramuscular or intravenous use.

Dosage Form

Spasfon is presented as a clear solution for injection, supplied in 4ml glass ampoules, packaged six to a box, each ampoule containing 40mg of Phloroglucinol hydrate and 0.04mg of Trimethylphloroglucinol, intended for intramuscular or intravenous administration.

Uses

Spasfon Injection is used for the symptomatic treatment of acute spasmodic pain arising from the intestine, biliary tract, bladder, and uterus. It is commonly prescribed for conditions such as renal colic, biliary colic, spasms of the sphincter of Oddi, ureteral spasms associated with kidney stones, and acute gynecological pain. It may also be used to help ease the passage of gallstones or kidney stones by relaxing the surrounding smooth muscle.

How to Use

Spasfon must be administered by a trained healthcare professional, either by direct intravenous injection or intramuscular injection. The usual dose is one ampoule given at the time of an acute spasm or crisis, which may be repeated if spasms are severe, without exceeding three ampoules within a 24-hour period. As there is no established compatibility data with other medications, Spasfon should not be mixed with other drugs in the same syringe or infusion. This medication should never be self-administered.

Side Effects

Spasfon is generally well tolerated, with a relatively favorable safety profile compared to many other antispasmodic medications. When side effects do occur, they may include mild injection site discomfort, nausea, or, in rare cases, allergic reactions such as skin rash. Because it does not act through anticholinergic pathways, it is less likely to cause effects like dry mouth, blurred vision, or urinary retention that are seen with older-generation antispasmodics. Any signs of a hypersensitivity reaction, such as swelling or difficulty breathing, require immediate medical attention.

Pregnancy & Breastfeeding

Spasfon is generally considered usable during pregnancy, except during the first trimester, when its use should be more carefully evaluated by a doctor. Animal studies have not shown evidence of a teratogenic effect from phloroglucinol. Its use during breastfeeding should still be discussed with a healthcare provider, as individual circumstances can vary, and it should only be used when a doctor confirms it is appropriate.

Storage Instructions

Spasfon ampoules should be stored at room temperature, below 25°C, away from direct sunlight and moisture. Keep the ampoules in their original packaging until ready for use, and store them safely out of the reach of children. Do not use any ampoule beyond its printed expiry date.

FAQs

What is Spasfon Injection used for?
It’s used to relieve acute spasmodic pain affecting the intestines, biliary tract, urinary tract, and gynecological system.
How is it different from anticholinergic antispasmodics?
Spasfon acts directly on smooth muscle rather than through nerve pathways, so it typically avoids side effects like dry mouth or blurred vision.
Can it be given during pregnancy?
It’s generally considered usable outside the first trimester, but a doctor should confirm suitability based on individual circumstances.
How much can be given in a day?
The usual dose is one ampoule per episode, repeated if needed, without exceeding three ampoules in 24 hours.

Disclaimer

Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.