Description

Description

Neoglip XR 50/1000mg is a combination antidiabetic medicine manufactured by ATCO Laboratories, formulated with Sitagliptin and extended-release Metformin Hydrochloride. This extended-release formulation gradually releases Metformin over time, offering steady blood sugar control with the convenience of once-daily dosing, while Sitagliptin works alongside it to enhance the body’s natural insulin response. Together, they provide more effective and consistent blood sugar management for patients with type 2 diabetes.

Ingredients

Each extended-release film-coated tablet of Neoglip XR contains:

• Sitagliptin – 50mg (a DPP-4 inhibitor)
• Metformin Hydrochloride (Extended-Release) – 1000mg (a biguanide)

Dosage Form

Neoglip XR 50/1000mg is available as oral extended-release film-coated tablets, packed 14 tablets per strip/box.

Uses

Neoglip XR 50/1000mg is commonly prescribed for:

• Management of type 2 diabetes mellitus requiring higher-strength, once-daily combination therapy
• Patients needing steady, sustained blood sugar control throughout the day
• Improved insulin response combined with reduced liver glucose production
• Supporting better glycemic control alongside diet and exercise, especially for those who prefer simplified once-daily dosing

How to Use

Neoglip XR should be taken exactly as directed by a registered physician, typically once daily with the evening meal, to help reduce the risk of stomach upset and support steady drug release. Swallow the tablet whole with a glass of water — do not crush, split, or chew it, as this can disrupt the extended-release mechanism and cause the medicine to be released too quickly. You may notice the empty tablet shell in your stool; this is normal and does not mean the medicine wasn’t absorbed. Continue to follow your prescribed diet and exercise plan, and do not stop treatment without consulting your doctor.

Side Effects

Common side effects that may occur with Neoglip XR include:

• Nausea or stomach upset
• Diarrhea
• Abdominal discomfort
• Headache
• Low blood sugar (hypoglycemia), especially when combined with other diabetes medicines
• Metallic taste in the mouth

Rarely, Metformin-containing medicines may cause a serious condition called lactic acidosis; seek immediate medical attention if you experience unusual muscle pain, difficulty breathing, or extreme tiredness.

Pregnancy & Breastfeeding

Neoglip XR is generally not recommended during pregnancy, as insulin is usually preferred for managing blood sugar levels in pregnant women with diabetes. It should only be used if a doctor determines it is clearly necessary. Use during breastfeeding should also be discussed with a physician, as safety data for this combination is limited.

Storage Instructions

Store Neoglip XR tablets below 30°C in a cool, dry place, away from direct sunlight and moisture. Keep the tablets in their original packaging until use, and store them out of reach of children.

FAQs

Q: Why is Neoglip XR taken only once daily?
A: The extended-release formulation gradually releases Metformin throughout the day, allowing for once-daily dosing while maintaining steady blood sugar control.

Q: Can I crush or split Neoglip XR tablets?
A: No, crushing or splitting can disrupt the extended-release mechanism, causing the medicine to release too quickly and increasing the risk of side effects.

Q: Is it normal to see something in my stool after taking Neoglip XR?
A: Yes, the tablet’s outer shell may appear in the stool after the medicine has been absorbed; this is a normal and expected part of how extended-release tablets work.

Disclaimer

Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.