Description

Description

Olesta AM (10/20mg) is a combination antihypertensive medicine manufactured by Searle, formulated with Amlodipine and Olmesartan Medoxomil as its active ingredients. This particular strength contains a higher dose of amlodipine compared to the standard formulation, making it suitable for patients who require stronger calcium channel blocking action alongside the angiotensin receptor blocking effect of olmesartan. This pack contains 20 tablets, combining 10mg of amlodipine with 20mg of olmesartan. Olesta AM (10/20mg) is commonly used for managing high blood pressure and preventing certain types of chest pain requiring more intensive vasodilating support.

Ingredients

Each Olesta AM tablet in this strength contains Amlodipine 10mg and Olmesartan Medoxomil 20mg. Amlodipine, present here at a higher dose, works by selectively inhibiting calcium ion influx across cell membranes, relaxing vascular smooth muscle more strongly and reducing peripheral resistance for a more pronounced blood pressure-lowering effect. Olmesartan Medoxomil works as an angiotensin II receptor blocker, preventing angiotensin II from binding to its receptors and inhibiting its vessel-constricting effects. Together, these two mechanisms provide a combined effect that is particularly effective for patients needing stronger vasodilation. The tablet also contains standard inactive excipients used for formulation and stability.

Dosage Form

Olesta AM is available as an oral, film-coated tablet, supplied in a pack of 20 tablets. This formulation, with its higher amlodipine dose, is intended for once-daily administration in patients requiring more intensive calcium channel blocking action.

Uses

Olesta AM (10/20mg) is primarily used to treat essential hypertension in adults who require stronger combination therapy, particularly those who benefit from a more pronounced vasodilating effect. It is also used to help prevent certain types of chest pain, known as angina, related to reduced blood flow to the heart. By combining a higher-strength calcium channel blocker with an angiotensin receptor blocker, this formulation supports more effective management of high blood pressure, helping reduce the risk of stroke, heart attack, and kidney complications.

How to Use

Olesta AM should be taken exactly as prescribed by a physician, generally as one tablet once daily, with or without food. The tablet should be swallowed whole with a glass of water, and taking it at the same time each day supports more consistent blood pressure control. Your doctor may suggest taking the first dose before bedtime, as it can cause dizziness initially. If you are also taking cholesterol-lowering resins such as cholestyramine, it’s advised to take this medicine at least four hours apart from those medications. Given the higher amlodipine strength, dosage should never be self-adjusted.

Side Effects

Because this strength contains a higher amlodipine dose, patients may be more likely to experience swelling in the feet, ankles, or lower legs, along with dizziness, headache, and flushing. Inflammation of the nose and throat, nausea, and stomach discomfort have also been reported. Because dizziness can occur, particularly with the first dose, caution is advised when driving or operating machinery. Periodic monitoring of potassium levels and kidney function is recommended during long-term use. Any severe or persistent symptoms should be reported to a doctor promptly.

Pregnancy & Breastfeeding

Olesta AM should not be used during pregnancy, as angiotensin receptor blockers like olmesartan carry known risks to fetal development, particularly during the second and third trimesters. Women who are pregnant or planning pregnancy should consult their doctor about safer alternatives. Breastfeeding mothers should also seek medical advice before using this medicine, as its safety during lactation has not been clearly established.

Storage Instructions

Store Olesta AM tablets below 30 degrees Celsius, in a cool, dry place, away from direct sunlight and moisture. Keep the tablets in their original packaging until ready for use to protect them from environmental exposure. Store the medicine out of reach of children and pets, and do not use tablets beyond their printed expiry date.

FAQS

How does this strength differ from the standard Olesta AM formulation?
It contains a higher amlodipine dose (10mg instead of 5mg), providing stronger vasodilating action for blood pressure control.

Why might swelling in the legs occur more often at this strength?
Higher amlodipine doses can increase the likelihood of fluid retention in the lower limbs, a known effect of calcium channel blockers.

Is this formulation suitable for first-time hypertension treatment?
No, it is typically prescribed for patients who require a stronger vasodilating effect after trying lower-dose options.

Can this medicine be used long-term?
Yes, it can be used for long-term management under continued medical supervision and periodic health checks.

Disclaimer

Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.