Description
Description
Tramal-D (75mg/25mg) is a combination pain-relief medicine formulated with Tramadol and Dexketoprofen as its active ingredients, manufactured by Searle. It combines a centrally-acting opioid analgesic with a fast-acting NSAID in a single tablet, designed to provide rapid and enhanced relief for moderate to severe pain. This pack contains 10 tablets, combining 75mg of tramadol with 25mg of dexketoprofen. Tramal-D is commonly used for managing musculoskeletal pain, post-operative pain, dental pain, and injury-related pain, working through complementary mechanisms to target both the pain signal and the underlying inflammation.
Ingredients
Each Tramal-D tablet contains Tramadol 75mg and Dexketoprofen 25mg. Tramadol acts on the central nervous system, binding to opioid receptors in the brain and spinal cord to reduce the perception of pain, while also enhancing the body’s natural pain-inhibiting pathways. Dexketoprofen, a nonsteroidal anti-inflammatory drug (NSAID), works by blocking the production of prostaglandins, chemicals responsible for pain and inflammation at the site of injury. Together, these two compounds provide rapid and enhanced pain relief, combining central and peripheral mechanisms for more comprehensive symptom control. The tablet also contains standard inactive excipients used for formulation and stability.
Dosage Form
Tramal-D is available as an oral tablet, supplied in a pack of 10 tablets. It is generally taken every six to eight hours depending on pain severity, based on the physician’s specific dosing instructions.
Uses
Tramal-D is primarily used for the management of moderate to severe pain, including musculoskeletal pain, post-operative pain, dental pain, and pain resulting from injury. Its dual-action formula makes it particularly useful for pain that involves both a strong inflammatory component and a need for central pain signal suppression, offering faster and more comprehensive relief than either medicine used alone.
How to Use
Tramal-D tablets should be taken exactly as prescribed by a physician, usually every six to eight hours depending on the severity of pain. The recommended daily dose should not be exceeded. The tablet should be swallowed whole with a glass of water, and it’s important to inform your doctor about all other medications you are currently taking to avoid potential interactions. If side effects persist or worsen, medical advice should be sought promptly rather than continuing self-treatment.
Side Effects
Common side effects of Tramal-D may include nausea, dizziness, drowsiness, and constipation, largely related to the opioid component. Because it also contains an NSAID, there is a potential risk of stomach discomfort or gastrointestinal irritation, particularly with prolonged use. Caution is advised when driving or operating machinery, as this medicine can cause sleepiness. Any signs of an allergic reaction or unusual symptoms should be reported to a doctor promptly, and this medicine should not be stopped abruptly after extended use to avoid withdrawal symptoms.
Pregnancy & Breastfeeding
Tramal-D should only be used during pregnancy if a doctor determines it is clearly necessary, as both the opioid and NSAID components require careful medical evaluation during this period. Breastfeeding mothers should also consult their doctor before using this medicine, as its components may pass into breast milk and affect a nursing infant.
Storage Instructions
Store Tramal-D tablets below 30°C, in a dry place, away from moisture and direct sunlight. Keep the tablets in their original packaging until ready for use to protect them from environmental exposure. Store the medicine securely out of reach of children and pets, and do not use tablets beyond their printed expiry date.
FAQS
Why does Tramal-D combine tramadol with dexketoprofen instead of paracetamol?
The combination with an NSAID like dexketoprofen targets inflammation directly, offering faster and more enhanced relief for pain with an inflammatory component.
How often can Tramal-D be taken?
It is generally taken every six to eight hours depending on pain severity, but the daily dose should never exceed what your doctor has prescribed.
Can Tramal-D be used for long-term pain management?
It is generally intended for short-term use, and any extended use should be closely monitored by a healthcare provider.
Does Tramal-D cause drowsiness?
Yes, it can cause sleepiness or drowsiness, so driving or operating machinery should be avoided until you know how it affects you.
Disclaimer
Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.






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