Description

Frendol-P (37.5/325mg) is a combination pain-relief tablet containing Tramadol Hydrochloride and Paracetamol, manufactured by High-Q Pharma. This formulation pairs an opioid analgesic with a non-opioid pain reliever and fever reducer, offering a dual-action approach to managing moderate to moderately severe pain. Tramadol works centrally on the brain to reduce the sensation of pain, while Paracetamol adds its own pain-relieving and fever-reducing effect, together often providing more effective relief than either ingredient alone. This medicine is commonly used for conditions such as musculoskeletal pain, post-surgical pain, dental pain, and other acute pain situations. Given its opioid content, this medicine carries a risk of tolerance and dependence, so it’s generally recommended for short-term, doctor-supervised use. The pack contains 10 tablets and is a controlled prescription medicine.

Ingredients

Each Frendol-P (37.5/325mg) tablet contains two active ingredients: Tramadol Hydrochloride 37.5mg, an opioid analgesic, and Paracetamol 325mg, a non-opioid analgesic and antipyretic. These are combined into a single tablet along with standard pharmaceutical excipients.

Dosage Form

This medicine is supplied as an oral tablet, meant to be swallowed whole with a full glass of water rather than crushed or chewed.

Uses

Frendol-P (37.5/325mg) is used to relieve moderate to moderately severe pain, including musculoskeletal pain, post-surgical pain, dental pain, and pain following injury. Tramadol acts on the central nervous system to reduce pain signaling, working alongside its effects on certain neurotransmitters, while paracetamol adds central pain-relieving and fever-reducing action. Together, this combination is intended to provide effective short-term pain relief while allowing for a comparatively lower dose of each individual ingredient than might otherwise be needed.

How to Use

Frendol-P should be taken exactly as directed by a doctor, with or without food, though taking it with food or milk can help reduce the risk of stomach-related side effects. The tablet should be swallowed whole with a full glass of water. This medicine should be used only for the duration recommended by your doctor, given the risk of tolerance and dependence associated with the tramadol component, and the prescribed dose should never be exceeded. It’s important to avoid taking this medicine alongside other paracetamol-containing products, to prevent accidental paracetamol overdose. If a dose is missed, take it as soon as remembered unless it’s close to your next scheduled dose, in which case skip the missed dose rather than doubling up.

Side Effects

Very commonly reported side effects include nausea, dizziness, and drowsiness. Other common effects include vomiting, constipation, flatulence, diarrhea, stomach pain, dry mouth, itching, sweating, headache, shaking, confusion, sleep disturbances, and mood changes such as anxiety or nervousness. Less commonly, more serious effects such as breathing difficulties, seizures, or signs of serotonin-related reactions can occur, and these should be treated as a medical concern requiring prompt attention. This medicine should be used with particular caution in people with a history of substance use disorder, seizures, respiratory conditions, or liver or kidney disease, and should never be combined with alcohol, sedatives, or other medicines that depress the central nervous system without a doctor’s explicit guidance.

Pregnancy & Breastfeeding

Frendol-P is generally not recommended during pregnancy, particularly for extended use, since opioid medicines can affect the developing baby and may cause withdrawal effects in a newborn if used close to delivery. This medicine should also be avoided while breastfeeding unless specifically approved by a doctor, as both tramadol and paracetamol can pass into breast milk. Anyone who is pregnant, planning a pregnancy, or breastfeeding should discuss safer pain management alternatives with their doctor before using this medicine.

Storage Instructions

Store Frendol-P tablets at room temperature, away from direct sunlight, heat, and moisture. Keep the tablets in their original packaging until needed, and store them securely out of reach of children and anyone for whom they aren’t prescribed, given the opioid content. Any expired or unused tablets should be disposed of properly rather than through household waste.

FAQs

Why shouldn’t I take this with other paracetamol-containing products?
Combining this medicine with other products containing paracetamol can lead to accidental overdose of that ingredient, which can seriously harm the liver.

Can this medicine be taken long-term?
It’s generally recommended for short-term use due to the risk of tolerance and dependence associated with the tramadol component — any longer-term need should be reassessed by your doctor.

Is it safe to drink alcohol while taking this medicine?
No, alcohol should be avoided entirely while taking this medicine, as combining it with opioid pain relievers can increase the risk of serious breathing problems.

What should I do if I suspect an overdose?
This should be treated as a medical emergency — seek immediate medical attention, as an overdose involving either ingredient can be serious.

Disclaimer

Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.