Description

Description

Avsar Plus 10/160/12.5mg is a film-coated triple-combination tablet manufactured by PharmaEvo, containing Amlodipine, Valsartan, and Hydrochlorothiazide as active ingredients. Each pack contains 28 tablets and represents the highest strength within the Avsar Plus range, generally reserved for adults whose blood pressure remains above target despite treatment with the lower-strength triple combination or other dual therapies. This formulation combines a higher dose of Amlodipine, a calcium channel blocker that relaxes blood vessel walls, with Valsartan, an angiotensin receptor blocker that prevents a hormone from narrowing blood vessels, and Hydrochlorothiazide, a mild diuretic that helps remove excess salt and water from the body. Bringing together these three mechanisms at a higher intensity offers a more powerful, multi-pathway approach for patients with persistently difficult-to-control hypertension. Avsar Plus 10/160/12.5mg is typically used under the close and ongoing supervision of a physician.

Ingredients

Avsar Plus 10/160/12.5mg contains three active ingredients: Amlodipine at a strength of 10mg, Valsartan at a strength of 160mg, and Hydrochlorothiazide at a strength of 12.5mg per tablet. The tablet also includes standard pharmaceutical excipients such as fillers, binding agents, and film-coating materials that support its shape, stability, and ease of swallowing. These inactive ingredients do not contribute to the therapeutic effect but are necessary for consistent manufacturing and storage quality.

Dosage Form

Avsar Plus 10/160/12.5mg is available as an oral film-coated tablet combining 10mg of Amlodipine, 160mg of Valsartan, and 12.5mg of Hydrochlorothiazide. The pack contains 28 tablets, generally supporting a full month’s supply when taken as a once-daily dose, as directed by the prescribing doctor.

Uses

Avsar Plus 10/160/12.5mg is primarily prescribed for adults with high blood pressure that has not been sufficiently controlled by the lower-strength triple combination or by other dual-therapy regimens. By combining higher doses of a calcium channel blocker, an angiotensin receptor blocker, and a diuretic, this medicine provides one of the most comprehensive combination approaches available for managing resistant hypertension. Achieving sustained blood pressure control at this level plays an important role in reducing the long-term risk of complications such as stroke, heart attack, and kidney-related damage.

How to Use

Avsar Plus 10/160/12.5mg is generally taken once daily, at around the same time each day, with or without food, exactly as instructed by the prescribing physician. The tablet should be swallowed whole with a glass of water and should not be crushed or chewed. Because this is the highest strength in the Avsar Plus range, it is especially important to follow the prescribed dose precisely, as it is typically reached gradually after a doctor has assessed the response to lower-strength combinations. Some patients may notice a mild increase in urination due to the diuretic component, particularly in the early stages of treatment. Treatment should be continued consistently, even when blood pressure feels well managed, since stopping the medicine abruptly can allow blood pressure to rise again.

Side Effects

At this highest strength, side effects reflect the combined actions of all three ingredients and may be more pronounced in some individuals compared with lower-dose combinations. Commonly reported effects include dizziness, headache, and fatigue. Swelling in the ankles or feet, along with flushing or a warm sensation in the skin, is associated with the higher Amlodipine dose, while increased urination, mild dehydration, or changes in electrolyte levels such as sodium and potassium relate to the diuretic component, making periodic blood tests an important part of ongoing monitoring. Other possible effects include nausea, muscle cramps, or a drop in blood pressure when standing up quickly, sometimes leading to lightheadedness. Signs of a serious allergic reaction, such as swelling of the face, lips, or throat, or an unusually fast or irregular heartbeat, should be treated as a medical emergency. Severe dizziness, fainting, or symptoms of significant electrolyte imbalance such as unusual weakness or confusion should be reported to a doctor promptly.

Pregnancy & Breastfeeding

Avsar Plus 10/160/12.5mg should not be used during pregnancy, as the Valsartan component carries a known risk of harm to the developing baby, particularly during the second and third trimesters, and the diuretic component may further affect fluid balance during pregnancy. Anyone who becomes pregnant while taking this medicine should inform their doctor immediately so that treatment can be reviewed and changed without delay. Breastfeeding while using this medicine is also generally not recommended, as it is not well established how these active ingredients may affect a nursing infant. Pregnant or breastfeeding individuals should discuss safer treatment alternatives with their doctor before starting or continuing this medicine.

Storage Instructions

Avsar Plus tablets should be stored in a cool, dry place, away from direct sunlight and excessive humidity, ideally at normal room temperature. Tablets should remain in their original packaging until ready for use to help preserve their effectiveness. As with all medicines, Avsar Plus must be stored out of the reach and sight of children.

FAQs

Why would a doctor prescribe this strength instead of the 5/160/12.5mg combination?
This strength is typically used when blood pressure remains above target on the lower-dose triple combination, and a doctor determines that a more intensive level of therapy is needed.

Is it safe to start treatment directly on this strength?
Usually not; this strength is generally reached gradually after a doctor has evaluated how the patient responds to lower doses, though individual circumstances may vary.

Will I need regular blood tests while taking this medicine?
Yes, periodic monitoring of kidney function, sodium, and potassium levels is generally recommended, given the diuretic component and the intensity of this combination.

What should I do if I miss a dose?
If a dose is missed, take it as soon as you remember, unless it is close to the time of your next dose, in which case skip the missed dose and continue with your regular schedule rather than doubling up.

Disclaimer

Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.