Description

Description

Daplozmet XR 10/500mg is a prescription medicine manufactured by Highnoon Laboratories, combining Dapagliflozin and Metformin in an extended-release tablet form. This fixed-dose combination brings together two complementary approaches to blood sugar management, with the Metformin component designed to release gradually over time rather than all at once. Dapagliflozin belongs to the sodium-glucose co-transporter 2 (SGLT2) inhibitor class, working by limiting glucose reabsorption in the kidneys and encouraging its excretion through urine. In this strength, Dapagliflozin is present at a higher level compared to some other combinations in the Daplozmet XR range, making it typically suited for patients whose treatment plan calls for a greater Dapagliflozin dose alongside a standard Metformin strength. Metformin, in its extended-release form, works mainly by reducing glucose production in the liver while improving the body’s response to insulin, with its gradual release profile intended to help reduce the gastrointestinal discomfort sometimes associated with immediate-release Metformin. Each pack of Daplozmet XR 10/500mg contains 14 tablets, produced under the quality standards maintained by Highnoon Laboratories.

Ingredients

Daplozmet XR 10/500mg contains two active ingredients: Dapagliflozin at a strength of 10 milligrams and Metformin Hydrochloride, in extended-release form, at a strength of 500 milligrams per tablet. The formulation also includes inactive excipients such as extended-release matrix-forming agents, binding materials, and film-coating components, which work together to control the gradual release of Metformin and support the tablet’s overall structural integrity. These excipients carry no therapeutic effect on their own but are essential to the tablet’s release mechanism and stability.

Dosage Form

Daplozmet XR 10/500mg is available as an oral extended-release film-coated tablet. Each pack contains 14 tablets, providing a supply suited to a once-daily combination treatment schedule as directed by a physician. Owing to its extended-release design, the tablet should be swallowed whole and must not be crushed, split, or chewed, as this could interfere with the controlled release mechanism.

Uses

Daplozmet XR 10/500mg is used to help improve blood sugar control in adults with type 2 diabetes mellitus, particularly where a physician determines that a higher Dapagliflozin dose alongside extended-release Metformin is appropriate for the patient’s individual treatment needs. It is generally used in conjunction with dietary changes and regular physical activity as part of a broader diabetes management plan. This medicine is not intended for individuals with type 1 diabetes or for the management of diabetic ketoacidosis. The suitability of this specific strength for any individual patient should always be confirmed through proper medical assessment.

How to Use

Daplozmet XR 10/500mg should be taken exactly as directed by a prescribing physician, typically once daily with the evening meal, which may help support tolerability and the intended extended-release action. The tablet must be swallowed whole with a glass of water and should never be crushed, split, or chewed, as doing so could disrupt the extended-release formulation and alter how the medicine is absorbed. Patients should continue to follow any dietary and lifestyle recommendations provided by their doctor and must never modify the dosage without medical advice. Regular monitoring of blood sugar levels and kidney function is typically recommended throughout treatment.

Side Effects

Daplozmet XR 10/500mg may cause side effects in some individuals, although not everyone will experience them. Commonly reported effects include gastrointestinal symptoms such as mild nausea, diarrhea, or stomach discomfort, which tend to be less pronounced with the extended-release formulation, though they can still occur, particularly during the initial period of treatment. Effects associated with the higher-strength Dapagliflozin component, such as urinary tract infections, genital yeast infections, and increased urination, may also be experienced, and some patients may notice these effects more than with lower Dapagliflozin doses. Mild dizziness or symptoms related to dehydration may also occur. A rare but serious risk linked to Metformin-containing medicines is lactic acidosis, which can present as unusual muscle pain, difficulty breathing, abdominal discomfort, or unexplained fatigue, requiring immediate medical attention if suspected. Patients with kidney or liver concerns, a history of heavy alcohol use, or those undergoing procedures involving contrast dye should inform their doctor before starting this medicine.

Pregnancy & Breastfeeding

The use of Daplozmet XR 10/500mg during pregnancy or breastfeeding should only occur under the specific direction of a qualified healthcare provider, as its suitability depends on individual clinical circumstances. Women who are pregnant, planning pregnancy, or breastfeeding should discuss their situation with their doctor before starting or continuing this combination medicine.

Storage Instructions

Daplozmet XR 10/500mg tablets should be stored in a cool, dry place away from direct sunlight and excess humidity, at the room temperature indicated on the packaging. Tablets should remain in their original blister pack until they are ready to be used, helping protect them from moisture and light exposure. Keep out of reach of children and pets, and avoid storage in areas with fluctuating temperatures such as bathrooms or vehicles.

FAQS

Q: How is Daplozmet XR 10/500mg different from the 5/500mg version?
It contains a higher strength of Dapagliflozin while keeping the same extended-release Metformin dose, and is typically prescribed when a greater Dapagliflozin dose is clinically needed.

Q: Can Daplozmet XR 10/500mg tablets be split or crushed?
No, the tablet should always be swallowed whole, as splitting or crushing can interfere with its extended-release mechanism.

Q: Should Daplozmet XR 10/500mg be taken at a specific time of day?
It is generally taken once daily with the evening meal, though the exact timing should follow the prescribing doctor’s instructions.

Q: Is more frequent monitoring needed with the higher Dapagliflozin strength?
Doctors may recommend closer monitoring of kidney function and hydration status with higher Dapagliflozin doses, depending on the individual patient’s health profile.

Disclaimer

Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.