Description

Description

Ampiclox (250mg) is a combination antibiotic capsule containing Ampicillin and Cloxacillin, manufactured by GlaxoSmithKline (GSK) Pakistan. Both ingredients belong to the penicillin group of antibiotics, and this pairing is specifically designed to be effective against a broader range of bacteria than either ingredient alone. Ampicillin works against many common gram-positive and gram-negative bacteria, while Cloxacillin is particularly effective against certain penicillin-resistant staphylococcal bacteria, since it resists being broken down by an enzyme (beta-lactamase) that some bacteria produce to defend themselves. This combination is commonly prescribed for infections of the respiratory tract, skin, ear, throat, and urinary tract, as well as certain soft tissue and bone infections. The pack contains 100 capsules and is generally intended for extended treatment courses or pharmacy and clinical supply, as directed by a doctor.

Ingredients

Each Ampiclox (250mg) capsule contains Ampicillin (as ampicillin trihydrate) 125mg and Cloxacillin (as cloxacillin sodium) 125mg, together totaling 250mg of combined active ingredients, along with standard pharmaceutical excipients that make up the capsule’s shell and filling.

Dosage Form

This medicine is supplied as an oral capsule, meant to be swallowed with water, generally with or without food, though your doctor’s specific instructions should be followed for best absorption.

Uses

Ampiclox (250mg) is used to treat a wide variety of bacterial infections affecting the respiratory tract, skin, ear, throat, urinary tract, stomach, and intestines. Ampicillin interferes with bacterial cell wall synthesis by binding to penicillin-binding proteins, preventing bacteria from forming the walls they need to survive, while Cloxacillin adds resistance against certain bacteria capable of destroying standard penicillins. Together, this combination is effective against a broad spectrum of gram-positive and gram-negative bacteria, making it a versatile option for many common bacterial infections.

How to Use

Ampiclox should be taken exactly as prescribed by a doctor, typically several times daily, with or without food. For adults, dosing is generally several capsules per day; for children, dosing is determined based on age and weight. The specific dosage, timing, and duration should always be determined by your doctor based on your condition and symptoms. It’s important to complete the full prescribed course, even if symptoms improve before the course is finished, since stopping early can allow the infection to persist or contribute to antibiotic resistance.

Side Effects

Side effects from Ampiclox are generally uncommon when the medicine is used as directed, but can include mild digestive upset, nausea, or diarrhea. Skin rash has also been reported in some patients. Any signs of a more serious allergic reaction, such as swelling of the face or throat, difficulty breathing, or widespread rash, should be treated as a medical emergency and require immediate attention. This medicine should not be taken alongside tetracycline antibiotics, and caution is advised if the patient has recently received a vaccination or has mononucleosis (glandular fever).

Pregnancy & Breastfeeding

Anyone who is pregnant or breastfeeding should consult their doctor before using Ampiclox, since the appropriateness of this combination during these periods depends on individual circumstances and the specific infection being treated. A healthcare provider can help determine whether this medicine is suitable or whether an alternative treatment might be preferred.

Storage Instructions

Store Ampiclox capsules in a cool, dry place, away from direct light and heat. Keep the medicine safely out of reach of children and pets. Any expired or unused capsules should be disposed of properly rather than kept or used past their intended shelf life.

FAQs

Why does this medicine combine two antibiotics instead of one?
Combining Ampicillin and Cloxacillin extends the range of bacteria this medicine can effectively treat, including certain penicillin-resistant bacteria that Ampicillin alone might not address.

Can this medicine be taken on an empty stomach?
It can generally be taken with or without food, but following your doctor’s specific instructions helps ensure the best absorption and effectiveness.

Should I avoid any other medicines while taking Ampiclox?
Yes, tetracycline-based antibiotics and medicines used for mononucleosis should not be taken at the same time as Ampiclox — always share your full medication list with your doctor.

Is this medicine effective against viral infections?
No, this medicine only works against bacterial infections and has no effect on viral illnesses such as the common cold or flu.

Disclaimer

Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.