Description
Description
Dioplus 5/80mg is a combination oral tablet manufactured by ATCO Laboratories, bringing together Amlodipine (5mg) and Valsartan (80mg) in a single dose. Packaged as 14 tablets per strip, it is formulated for patients whose blood pressure needs to be managed through two complementary mechanisms rather than a single-agent approach.
Ingredients
Each tablet contains Amlodipine Besylate 5mg, a calcium channel blocker, and Valsartan 80mg, an angiotensin II receptor blocker, along with standard pharmaceutical excipients that support tablet stability and absorption.
Dosage Form
Dioplus is supplied as a film-coated oral tablet, packed 14 tablets to a strip, intended to be swallowed whole with water.
Uses
Dioplus 5/80mg is prescribed for the management of hypertension (high blood pressure), particularly in patients who are not adequately controlled on a single blood pressure medicine alone. By combining two different mechanisms of action, it helps lower blood pressure more effectively, which in turn supports reduced risk of complications such as stroke, heart attack, and kidney strain associated with long-term uncontrolled hypertension.
How to Use
Take one tablet daily, generally at the same time each day, with or without food, exactly as directed by your physician. Swallow the tablet whole with a glass of water; do not crush or chew it. If a dose is missed, take it as soon as remembered unless it is close to the time of the next scheduled dose, in which case the missed dose should be skipped rather than doubled. Consistent daily timing helps maintain steady blood pressure control.
Side Effects
Commonly reported effects include swelling of the ankles or feet, headache, dizziness, and fatigue, particularly when treatment begins. Some patients experience flushing, low blood pressure symptoms such as lightheadedness on standing, or mild gastrointestinal discomfort. Less frequently, a rapid heartbeat or allergic skin reactions may occur. Any severe swelling, fainting, or difficulty breathing warrants immediate medical attention.
Pregnancy & Breastfeeding
Dioplus is not recommended during pregnancy, as medicines acting on the angiotensin system can affect fetal development, particularly in the second and third trimesters. It is also generally advised against during breastfeeding. Women who are pregnant, planning pregnancy, or nursing should consult their doctor immediately for an alternative treatment plan.
Storage Instructions
Store Dioplus tablets at room temperature, away from direct sunlight, heat, and moisture. Keep the strip inside its original packaging until the dose is needed, and store safely out of children’s reach. Do not use tablets past their expiry date.
FAQs
Why combine Amlodipine and Valsartan in one tablet? The two medicines work through different pathways, so combining them often lowers blood pressure more effectively than either used alone, while also simplifying the daily dosing routine.
Can Dioplus be stopped once blood pressure is under control? No, hypertension usually requires ongoing management, and stopping suddenly without medical advice can cause blood pressure to rise again.
Does salt intake affect how well this medicine works? Yes, a high-sodium diet can reduce its effectiveness, so following your doctor’s dietary advice alongside treatment is important.
Is ankle swelling a serious side effect? Mild swelling is a known effect of the amlodipine component and is usually manageable, but significant or painful swelling should be reported to your doctor.
Disclaimer
Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.






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