Description
Description
Adrance-M (5/500Mg) is a combination antidiabetic tablet containing Empagliflozin (5mg) and Metformin (500mg), manufactured by Atco Laboratories. It combines two mechanisms of action: Empagliflozin, an SGLT2 inhibitor, helps remove excess glucose through urine, while Metformin, a biguanide, reduces glucose production in the liver and improves insulin sensitivity. Each pack contains 14 tablets, offering a lower-strength combination option suitable for patients beginning combination therapy or requiring a gentler starting dose.
Ingredients
Each tablet contains 5mg of Empagliflozin and 500mg of Metformin, along with standard pharmaceutical excipients that support tablet formulation and stability.
Dosage Form
Adrance-M is available as an oral tablet, taken by mouth with a full glass of water, preferably with a meal.
Uses
Adrance-M is used, alongside diet and exercise, to improve blood sugar control in adults with type 2 diabetes requiring combination therapy. It also supports cardiovascular and kidney health benefits associated with Empagliflozin, and helps improve the body’s response to insulin through Metformin. It is not recommended for individuals with type 1 diabetes.
How to Use
Take one tablet daily, or as directed by your healthcare provider, preferably with a meal to enhance absorption and reduce stomach upset. Swallow the tablet whole with a full glass of water; do not break, crush, or chew it. Take the medication consistently at the same time each day for the best results.
Side Effects
Common side effects may include nausea, diarrhea, increased urination, or urinary tract infections. Less commonly, individuals may experience indigestion, abdominal discomfort, or headache. Rare but serious effects can include lactic acidosis (associated with Metformin) or diabetic ketoacidosis (associated with Empagliflozin). Seek immediate medical attention if you experience severe abdominal pain, unusual tiredness, or difficulty breathing.
Pregnancy & Breastfeeding
Adrance-M is contraindicated during pregnancy and breastfeeding. Consult your doctor for suitable alternatives if you are pregnant, planning pregnancy, or breastfeeding.
Storage Instructions
Store Adrance-M in a cool, dry place away from direct sunlight and moisture. Keep out of reach of children, and do not use beyond the expiry date printed on the packaging.
FAQs
What if I miss a dose?
Take it as soon as you remember; if it’s almost time for your next dose, skip the missed one and continue your regular schedule without doubling up.
Who should avoid Adrance-M?
Individuals with severe kidney impairment, those on dialysis, or patients with a history of diabetic ketoacidosis should not use this medication. It’s also unsuitable for those with a known allergy to either active ingredient.
Why might a doctor start with the 5mg Empagliflozin dose?
Lower starting doses can help assess tolerance before increasing to a higher strength if further blood sugar control is needed.
Does Adrance-M help with weight management?
It may assist in modest weight loss due to the glucose-excretion effect of Empagliflozin, though it’s not intended as a primary weight-loss treatment.
Disclaimer
Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.


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