Description

Description

Avsar Plus 10/160/25mg is a film-coated triple-combination tablet manufactured by PharmaEvo, containing Amlodipine, Valsartan, and Hydrochlorothiazide as active ingredients. Each pack contains 28 tablets and represents the highest overall strength in the Avsar Plus range, featuring an increased dose of the diuretic component compared with the 10/160/12.5mg formulation. This version is generally reserved for adults with more resistant or persistent high blood pressure that has not responded adequately to lower-dose triple combinations. The formulation brings together Amlodipine, a calcium channel blocker that relaxes blood vessel walls, Valsartan, an angiotensin receptor blocker that prevents a hormone from narrowing blood vessels, and a higher dose of Hydrochlorothiazide, a diuretic that helps the body eliminate excess salt and water. Together, these three mechanisms provide one of the most intensive combination approaches available for managing hypertension that has proven difficult to control with standard therapy. This medicine is typically used under close, ongoing supervision by a physician.

Ingredients

Avsar Plus 10/160/25mg contains three active ingredients: Amlodipine at a strength of 10mg, Valsartan at a strength of 160mg, and Hydrochlorothiazide at a strength of 25mg per tablet. The tablet also includes standard pharmaceutical excipients such as fillers, binding agents, and film-coating materials that support its shape, stability, and ease of swallowing. These inactive ingredients do not contribute to the therapeutic effect but are necessary for consistent manufacturing and storage quality.

Dosage Form

Avsar Plus 10/160/25mg is available as an oral film-coated tablet combining 10mg of Amlodipine, 160mg of Valsartan, and 25mg of Hydrochlorothiazide. The pack contains 28 tablets, generally supporting a full month’s supply when taken as a once-daily dose, as directed by the prescribing doctor.

Uses

Avsar Plus 10/160/25mg is primarily prescribed for adults with high blood pressure that remains inadequately controlled despite treatment with lower-strength triple combinations, including the 10/160/12.5mg formulation. The increased diuretic dose in this version is intended to provide additional fluid-related blood pressure control for patients who need it, working alongside the calcium channel blocker and angiotensin receptor blocker components. Achieving sustained control at this level of therapy plays an important role in reducing the long-term risk of complications such as stroke, heart attack, and kidney-related damage.

How to Use

Avsar Plus 10/160/25mg is generally taken once daily, at around the same time each day, with or without food, exactly as instructed by the prescribing physician. The tablet should be swallowed whole with a glass of water and should not be crushed or chewed. Given that this is the most intensive strength in the Avsar Plus range, it is especially important to follow the prescribed dose exactly, as it is typically reached only after a doctor has carefully assessed the response to lower-strength combinations. Some patients may notice a more noticeable increase in urination due to the higher diuretic dose, particularly in the early stages of treatment. Treatment should be continued consistently, even when blood pressure feels well managed, since stopping the medicine abruptly can allow blood pressure to rise again.

Side Effects

At this highest strength, side effects reflect the combined actions of all three ingredients and, due to the increased diuretic dose, may include a more noticeable degree of increased urination, mild dehydration, or shifts in electrolyte levels such as sodium and potassium, making regular blood tests an especially important part of ongoing monitoring. Other commonly reported effects include dizziness, headache, and fatigue. Swelling in the ankles or feet, along with flushing or a warm sensation in the skin, is associated with the Amlodipine component. Some patients may also experience nausea, muscle cramps, or a drop in blood pressure when standing up quickly, sometimes leading to lightheadedness. Signs of a serious allergic reaction, such as swelling of the face, lips, or throat, or an unusually fast or irregular heartbeat, should be treated as a medical emergency. Severe dizziness, fainting, or symptoms of significant electrolyte imbalance such as unusual weakness or confusion should be reported to a doctor promptly.

Pregnancy & Breastfeeding

Avsar Plus 10/160/25mg should not be used during pregnancy, as the Valsartan component carries a known risk of harm to the developing baby, particularly during the second and third trimesters, and the higher diuretic dose may further affect fluid balance during pregnancy. Anyone who becomes pregnant while taking this medicine should inform their doctor immediately so that treatment can be reviewed and changed without delay. Breastfeeding while using this medicine is also generally not recommended, as it is not well established how these active ingredients may affect a nursing infant. Pregnant or breastfeeding individuals should discuss safer treatment alternatives with their doctor before starting or continuing this medicine.

Storage Instructions

Avsar Plus tablets should be stored in a cool, dry place, away from direct sunlight and excessive humidity, ideally at normal room temperature. Tablets should remain in their original packaging until ready for use to help preserve their effectiveness. As with all medicines, Avsar Plus must be stored out of the reach and sight of children.

FAQs

How is this different from the 10/160/12.5mg strength?
This version contains a higher dose of Hydrochlorothiazide (25mg instead of 12.5mg), providing a stronger diuretic effect for patients who need additional fluid-related blood pressure control.

Who is typically prescribed this strength?
It is generally reserved for patients with resistant hypertension whose blood pressure remains above target despite treatment with lower-dose triple combinations, based on a doctor’s assessment.

Will I need more frequent blood tests on this strength?
Yes, given the higher diuretic dose, regular monitoring of kidney function, sodium, and potassium levels is particularly important throughout treatment.

What should I do if I miss a dose?
If a dose is missed, take it as soon as you remember, unless it is close to the time of your next dose, in which case skip the missed dose and continue with your regular schedule rather than doubling up.

Disclaimer

Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.