Description

Description

Blokium DIU (100mg/25mg) is an oral combination medicine manufactured by Highnoon Laboratories, supplied in a pack of 20 tablets. Each tablet pairs two ingredients that approach blood pressure control from different directions: Atenolol, a cardioselective beta-blocker that acts preferentially on beta receptors in the heart, and Chlorthalidone, a long-acting diuretic that helps the body eliminate excess sodium and water through increased urine output. Atenolol works by slowing the heart rate and reducing the force of each heartbeat, easing the overall strain on the heart, while Chlorthalidone reduces blood pressure by lowering the volume of fluid circulating in the blood vessels. This higher strength, with double the Atenolol and double the Chlorthalidone found in the 50mg/12.5mg version, is generally reserved for patients whose blood pressure needs a stronger combined effect, often after the lower-strength combination hasn’t achieved the desired result. Blokium DIU-100 should always be used strictly under a doctor’s supervision, given the additional considerations that come with combining a beta-blocker and a diuretic at this higher dose.

Ingredients

Each Blokium DIU-100 tablet contains Atenolol B.P. 100mg together with Chlorthalidone B.P. 25mg, forming a fixed-dose combination of the two active pharmaceutical ingredients. Additional details on the tablet’s excipients and formulation can be found on the leaflet included in the pack or obtained directly from Highnoon Laboratories.

Dosage Form

Blokium DIU-100 is presented as an oral tablet, packaged in blister strips totaling 20 tablets per box. This higher strength combines both active ingredients into a single tablet, allowing patients who need a stronger combined effect to manage their treatment with one dose rather than two separate medicines.

Uses

Blokium DIU-100 is prescribed for the treatment of hypertension, particularly in patients whose blood pressure requires a stronger combined effect of reduced heart workload and reduced fluid volume than the lower-strength combination provides. It is also used in patients with angina pectoris, where lowering the heart’s oxygen demand can help ease chest pain during exertion. This strength is generally considered by a doctor once a patient’s response to a lower dose of the same combination, or to Atenolol alone, has been assessed and found insufficient to reach the desired blood pressure target.

How to Use

Blokium DIU-100 tablets are generally taken once daily, at around the same time each day, as directed by the prescribing doctor. The tablet can usually be taken with or without food and should be swallowed with a glass of water. Because Chlorthalidone increases urine output, taking the dose earlier in the day is often preferred to avoid disrupting sleep with nighttime bathroom trips, though the exact timing should follow the doctor’s advice. Patients on this medicine are generally advised to drink enough water throughout the day to help offset the diuretic effect and reduce the risk of dehydration, and regular monitoring of blood pressure, kidney function, and electrolyte levels is often part of ongoing care at this strength. This medicine should never be stopped suddenly without medical advice, since abruptly discontinuing the beta-blocker component, particularly at this higher dose, can cause a pronounced rebound rise in heart rate or blood pressure; any change in dose or discontinuation should always be done gradually under a doctor’s guidance.

Side Effects

Blokium DIU-100 is generally well tolerated, but as with any combination of a beta-blocker and a diuretic, side effects can occur, and some may be more pronounced at this higher strength. Commonly reported effects include dizziness, lightheadedness, tiredness, and increased urination. Some patients may also notice cold hands or feet, mild nausea, or changes in electrolyte levels such as sodium or potassium, which is why periodic blood tests are particularly important during treatment at this dose. Diabetic patients should be aware that beta-blockers like Atenolol can mask some of the usual warning signs of low blood sugar, so extra attention to blood sugar monitoring is often advised. Less commonly, more pronounced effects such as marked low blood pressure, significant slowing of the heart rate, or sensitivity reactions in patients with a history of allergies or asthma can occur, and these should be reported to a doctor promptly. Alcohol is generally best avoided, as it can increase dizziness and drowsiness while taking this medicine.

Pregnancy & Breastfeeding

Blokium DIU-100 should not be used during pregnancy or while breastfeeding. Both the beta-blocker and diuretic components carry specific risks in these situations, including potential effects on an unborn baby or a nursing infant. Anyone who is pregnant, planning a pregnancy, or breastfeeding should inform their doctor so that an alternative treatment can be considered.

Storage Instructions

Blokium DIU-100 tablets should be stored at room temperature, away from direct sunlight, excess heat, and moisture. Keep the strip in its original packaging until a dose is needed, and store the medicine well out of the reach and sight of children. Tablets that have passed their printed expiry date should not be used and should be disposed of responsibly rather than placed in regular household waste.

FAQs

Is Blokium DIU-100 available without a prescription?
No, it is a prescription medicine and should only be used under a doctor’s supervision.

Why would a doctor prescribe DIU-100 instead of DIU-50?
The higher strength is generally used when the lower-dose combination hasn’t achieved adequate blood pressure control, based on the doctor’s assessment.

Can I stop taking Blokium DIU-100 once my blood pressure improves?
No, it should never be stopped suddenly, especially at this higher strength, as this can cause a pronounced rebound in heart rate or blood pressure.

Is Blokium DIU-100 safe for diabetic patients?
It can be used with caution, but since it may mask signs of low blood sugar, closer blood sugar monitoring is often recommended.

Why might I need blood tests while taking this medicine?
Periodic tests help monitor electrolyte levels, kidney function, and overall response, since the diuretic component can affect sodium and potassium levels, particularly at this higher strength.

Disclaimer

Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.