Description
Description
Clotnil Plus (75/75mg) is an oral tablet that combines Clopidogrel and Aspirin, two antiplatelet agents working together to reduce the risk of blood clots in patients with cardiovascular conditions. Manufactured by Barrett Hodgson Pakistan, this dual-therapy formulation is commonly prescribed for individuals recovering from a heart attack, stroke, or those managing unstable angina, where a combined antiplatelet approach offers stronger protection than a single agent alone. Each pack contains 10 tablets, produced under strict pharmaceutical quality standards to ensure consistent strength and reliability. By addressing platelet aggregation through two different mechanisms, Clotnil Plus helps maintain smoother blood flow and reduces the likelihood of clot-related complications.
Ingredients
Each Clotnil Plus (75/75mg) tablet contains two active ingredients: Clopidogrel (75mg) and Aspirin (75mg). Clopidogrel works by preventing platelets from sticking together, while Aspirin, a well-known NSAID, reduces the production of substances involved in clot formation and inflammation. The tablet also contains standard inactive excipients that support its structure, stability, and consistent absorption, without contributing any therapeutic effect themselves.
Dosage Form
Clotnil Plus (75/75mg) is available as a film-coated oral tablet, supplied in a strip format totaling 10 tablets per pack. It is intended for once-daily oral use.
Uses
Clotnil Plus (75/75mg) is primarily used to prevent heart attacks and strokes in patients with existing heart disease, peripheral vascular disease, or a recent stroke. It is also prescribed for the management of chest pain related to unstable angina or a recent heart attack, and to help keep blood vessels open following certain cardiac procedures, such as stent placement. This combination is typically chosen when a single antiplatelet medication does not provide sufficient protection against clot formation.
How to Use
Clotnil Plus (75/75mg) is generally taken once daily, at the same time each day to help maintain consistent effectiveness. It’s often recommended to take it with meals or a large volume of water or milk to help reduce the chance of stomach irritation from the Aspirin component. The tablet should be swallowed whole and not crushed or chewed unless specifically advised otherwise. This medication should not be stopped abruptly, particularly if prescribed after a stent procedure, without first consulting the prescribing doctor.
Side Effects
Clotnil Plus (75/75mg) may cause side effects related to its combined blood-thinning action. Commonly reported effects include an increased tendency to bruise or bleed, stomach discomfort or indigestion, headache, and dizziness. Some patients may also experience nosebleeds or, less frequently, a reduced platelet count. Any signs of unusual bleeding, black or bloody stools, or prolonged bleeding from minor cuts should be reported to a doctor without delay, as these may signal a more serious reaction.
Pregnancy & Breastfeeding
Clotnil Plus (75/75mg) is generally not recommended during pregnancy, particularly in the later stages, due to the Aspirin component’s potential effects on the fetus and delivery process. Its use during breastfeeding should also be discussed with a doctor, as both active ingredients may pass into breast milk in small amounts. A healthcare provider will assess the potential risks and benefits before recommending its use during these periods.
Storage Instructions
Store Clotnil Plus tablets at room temperature, in a cool, dry place away from direct sunlight and moisture. Keep the tablets in their original packaging until ready for use, and store them safely out of the reach of children. Do not use tablets that have passed their expiry date, and dispose of any unused or expired medicine responsibly.
FAQs
Q1: Why does this tablet combine Clopidogrel with Aspirin?
Combining the two provides stronger antiplatelet protection by targeting clot formation through two separate mechanisms, which can be especially useful after cardiac events or stent placement.
Q2: Can this medication be taken long-term?
Yes, it is often prescribed for extended periods, particularly after a stent procedure, but the exact duration should always be determined by a doctor.
Q3: What happens if a dose is missed?
Take it as soon as remembered, but if it’s nearly time for the next dose, skip the missed one rather than doubling up.
Q4: Does this medicine increase bleeding risk before surgery?
Yes, it can increase bleeding risk, so it’s important to inform your doctor about this medication well ahead of any planned surgical procedure.
Disclaimer
Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.






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