Description

Description

Co-Olesta (20/12.5mg) is a combination antihypertensive medicine manufactured by Searle, formulated with Olmesartan Medoxomil and Hydrochlorothiazide as its two active ingredients. It brings together an angiotensin II receptor blocker and a thiazide diuretic in a single tablet, offering a dual-action approach to managing high blood pressure. This pack contains 10 tablets, intended for once-daily use in adults who need combination therapy for effective blood pressure control. Co-Olesta works by relaxing and widening blood vessels while also helping the body eliminate excess sodium and water, together supporting healthier blood pressure levels and reduced cardiovascular risk.

Ingredients

Each Co-Olesta tablet contains Olmesartan Medoxomil 20mg and Hydrochlorothiazide 12.5mg. Olmesartan works by selectively blocking angiotensin II receptors, preventing the hormone from constricting blood vessels, which allows them to relax and widen for smoother blood flow. Hydrochlorothiazide acts as a diuretic, increasing the excretion of sodium and water through urine, which reduces blood volume and further lowers blood pressure. Together, these two compounds provide a synergistic effect for more comprehensive hypertension management. The tablet also contains standard inactive excipients used for binding, coating, and formulation stability.

Dosage Form

Co-Olesta is available as an oral, film-coated tablet, supplied in a pack of 10 tablets. It is intended for once-daily administration, offering a simplified routine for patients who require dual combination therapy for blood pressure control.

Uses

Co-Olesta is primarily used to treat essential hypertension in adults who require combination therapy rather than a single antihypertensive agent. By lowering high blood pressure, it helps reduce the risk of related complications such as stroke, heart attack, and kidney problems. Co-Olesta may also offer supportive benefit in reducing strain associated with certain heart conditions, contributing to better long-term cardiovascular protection when used as part of an overall treatment plan.

How to Use

Co-Olesta should be taken exactly as prescribed by a physician, generally as one tablet once daily, with or without food. The tablet should be swallowed whole with a glass of water, and maintaining a consistent daily schedule supports more stable blood pressure control. If you are also taking cholesterol-lowering resins such as cholestyramine, it’s advised to take Co-Olesta several hours apart from those medicines to avoid reduced absorption. Any dosage adjustments should only be made under medical supervision.

Side Effects

Common side effects associated with Co-Olesta include dizziness, headache, fatigue, and mild swelling caused by fluid retention. Some patients may also experience joint pain, back pain, or flu-like symptoms. Because the medicine includes a diuretic component, it can occasionally lead to dehydration, so adequate fluid intake is important during treatment. Diabetic patients should monitor their blood glucose levels closely, as Co-Olesta may influence sugar control. Any prolonged diarrhea, chest pain, palpitations, or persistent symptoms should be reported to a doctor promptly.

Pregnancy & Breastfeeding

Co-Olesta is generally not recommended for use during pregnancy, as angiotensin receptor blockers like olmesartan carry known risks to fetal development, particularly in the second and third trimesters. Women who are pregnant or planning pregnancy should consult their doctor about safer alternatives. Breastfeeding mothers should also seek medical advice before using this medicine, as its safety during lactation has not been clearly established.

Storage Instructions

Store Co-Olesta tablets at room temperature, away from direct sunlight, moisture, and excessive heat. Keep the tablets in their original packaging until ready for use to protect them from environmental exposure. Store the medicine out of reach of children and pets, and do not use tablets beyond their printed expiry date.

FAQS

Can Co-Olesta be taken with food?
Yes, it can be taken with or without food, based on personal preference or your doctor’s advice.

Why does Co-Olesta cause increased urination?
This is due to the diuretic component, hydrochlorothiazide, which helps the body remove excess sodium and water.

Is Co-Olesta suitable for diabetic patients?
It should be used with caution in diabetic patients, and blood glucose levels should be monitored regularly during treatment.

What should I avoid while taking Co-Olesta?
It’s best to avoid excessive alcohol intake and exercising in hot weather, as these can increase the risk of dehydration and dizziness.

Disclaimer

Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.