Description

Description

Co-Olesta AM (20/5/12.5mg) is a triple-combination antihypertensive medicine manufactured by Searle, formulated with Olmesartan Medoxomil, Amlodipine, and Hydrochlorothiazide as its active ingredients. This formulation brings together an angiotensin II receptor blocker, a calcium channel blocker, and a thiazide diuretic in a single tablet, offering a more comprehensive approach to blood pressure management for patients who need multiple mechanisms of action. This pack contains 14 tablets, intended for once-daily use in adults whose hypertension requires stronger combination therapy. Together, these three active ingredients relax blood vessels, prevent vessel-tightening effects, and help the body eliminate excess sodium and water.

Ingredients

Each Co-Olesta AM tablet contains Olmesartan Medoxomil 20mg, Amlodipine 5mg, and Hydrochlorothiazide 12.5mg. Olmesartan works by selectively blocking angiotensin II receptors, preventing blood vessel constriction and supporting smoother circulation. Amlodipine, a calcium channel blocker, relaxes blood vessels and improves blood flow while reducing the workload on the heart. Hydrochlorothiazide acts as a diuretic, promoting the excretion of sodium and water to reduce blood volume. Together, these three compounds provide a combined effect that supports more effective blood pressure control than any single agent alone. The tablet also contains standard inactive excipients used for formulation and stability.

Dosage Form

Co-Olesta AM is available as an oral, film-coated tablet, supplied in a pack of 14 tablets. It is intended for once-daily administration, offering a simplified routine for patients who require triple combination therapy for effective hypertension management.

Uses

Co-Olesta AM is primarily used to treat essential hypertension in adults who require combination therapy involving three different mechanisms of blood pressure control, particularly those who haven’t achieved adequate results with dual therapy alone. By combining an angiotensin receptor blocker, a calcium channel blocker, and a diuretic, this medicine helps manage more resistant or harder-to-control cases of high blood pressure, supporting reduced long-term risk of stroke, heart attack, and other cardiovascular complications.

How to Use

Co-Olesta AM should be taken exactly as prescribed by a physician, generally as one tablet once daily, with or without food. The tablet should be swallowed whole with a glass of water, and maintaining a consistent daily schedule supports more stable blood pressure control. If you are also taking cholesterol-lowering resins such as cholestyramine, it’s advised to take this medicine several hours apart from those medications. Any dosage adjustments should only be made under medical supervision, and the medicine should not be stopped abruptly without consulting a doctor.

Side Effects

Common side effects associated with Co-Olesta AM include dizziness, headache, fatigue, and swelling in the ankles, feet, or lower limbs. Some patients may also experience joint pain, back pain, or flu-like symptoms. Because the medicine includes a diuretic component, it can occasionally lead to dehydration or electrolyte imbalances, so adequate fluid intake and periodic monitoring are important. Diabetic patients should keep close track of their blood glucose levels, as this combination may influence sugar control. Any severe or persistent symptoms, including chest pain, palpitations, or significant drops in blood pressure, should be reported to a doctor immediately.

Pregnancy & Breastfeeding

Co-Olesta AM is generally not recommended for use during pregnancy, as angiotensin receptor blockers like olmesartan carry known risks to fetal development, particularly during the second and third trimesters. Women who are pregnant or planning pregnancy should consult their doctor about safer alternatives. Breastfeeding mothers should also seek medical advice before using this medicine, as its safety during lactation has not been clearly established.

Storage Instructions

Store Co-Olesta AM tablets at room temperature, away from direct sunlight, moisture, and excessive heat. Keep the tablets in their original packaging until ready for use to protect them from environmental exposure. Store the medicine out of reach of children and pets, and do not use tablets beyond their printed expiry date.

FAQS

Why does Co-Olesta AM combine three different medicines?
It combines an angiotensin receptor blocker, a calcium channel blocker, and a diuretic to provide more comprehensive blood pressure control for harder-to-manage hypertension.

Can Co-Olesta AM be taken with food?
Yes, it can be taken with or without food, based on your doctor’s guidance.

Is regular monitoring required during treatment?
Yes, periodic checks of blood pressure, kidney function, and electrolyte levels are often recommended.

Is Co-Olesta AM suitable for first-time hypertension treatment?
No, it is typically prescribed for patients who require triple therapy after other combinations haven’t achieved adequate control.

Disclaimer

Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.