Description

Description

Daplozmet XR 5/500mg is a prescription medicine manufactured by Highnoon Laboratories, combining Dapagliflozin and Metformin in an extended-release tablet form. This fixed-dose combination brings together two complementary approaches to blood sugar management, formulated to release its Metformin component gradually over time rather than all at once. Dapagliflozin belongs to the sodium-glucose co-transporter 2 (SGLT2) inhibitor class, working by limiting glucose reabsorption in the kidneys and encouraging its excretion through urine. Metformin, present here in its extended-release form, belongs to the biguanide class and works mainly by reducing glucose production in the liver while improving the body’s response to insulin. The extended-release design of the Metformin component is intended to provide a steadier release profile throughout the day, which can help reduce the frequency of gastrointestinal discomfort that is sometimes associated with immediate-release Metformin formulations. Each pack of Daplozmet XR 5/500mg contains 14 tablets, produced under the quality standards maintained by Highnoon Laboratories.

Ingredients

Daplozmet XR 5/500mg contains two active ingredients: Dapagliflozin at a strength of 5 milligrams and Metformin Hydrochloride, in extended-release form, at a strength of 500 milligrams per tablet. The formulation also includes inactive excipients such as extended-release matrix-forming agents, binding materials, and film-coating components, which work together to control the gradual release of Metformin and maintain the tablet’s structural integrity. These excipients do not have therapeutic activity themselves but play an essential role in the tablet’s release mechanism and overall stability.

Dosage Form

Daplozmet XR 5/500mg is available as an oral extended-release film-coated tablet. Each pack contains 14 tablets, providing a supply suited to a once-daily combination treatment schedule as directed by a physician. Owing to its extended-release design, the tablet is intended to be swallowed whole and should not be crushed, split, or chewed, as doing so could interfere with the controlled release mechanism.

Uses

Daplozmet XR 5/500mg is used to help improve blood sugar control in adults with type 2 diabetes mellitus, particularly in cases where a physician determines that combination therapy with an extended-release Metformin component is appropriate. It is generally used alongside dietary changes and regular physical activity as part of an overall diabetes management plan. This medicine is not intended for individuals with type 1 diabetes or for the management of diabetic ketoacidosis. The suitability of this extended-release combination for any individual patient should always be assessed by a qualified healthcare provider.

How to Use

Daplozmet XR 5/500mg should be taken exactly as prescribed by a physician, typically once daily with the evening meal, which may help improve tolerability and support the intended extended-release action. The tablet must be swallowed whole with a glass of water and should never be crushed, split, or chewed, as this could disrupt the extended-release formulation and alter how the medicine is absorbed. Patients should continue following any dietary or lifestyle guidance given by their doctor and must not adjust the dosage without medical advice. Regular monitoring of blood sugar levels and kidney function is typically recommended while using this medicine.

Side Effects

Daplozmet XR 5/500mg may cause side effects in some individuals, though not everyone experiences them. Commonly reported effects include gastrointestinal symptoms such as mild nausea, diarrhea, or stomach discomfort, which tend to be less pronounced with the extended-release formulation compared to immediate-release versions, though they can still occur, particularly when treatment is first started. Effects linked to the Dapagliflozin component, such as urinary tract infections, genital yeast infections, and increased urination, may also be experienced. Some patients may notice mild dizziness or symptoms related to dehydration. A rare but serious risk associated with Metformin-containing medicines is lactic acidosis, which can present as unusual muscle pain, difficulty breathing, abdominal discomfort, or unexplained tiredness, requiring immediate medical attention if suspected. Patients with kidney or liver concerns, a history of heavy alcohol use, or those undergoing procedures involving contrast dye should inform their doctor before starting this medicine.

Pregnancy & Breastfeeding

The use of Daplozmet XR 5/500mg during pregnancy or breastfeeding should only occur under the specific direction of a qualified healthcare provider, as its suitability depends on individual clinical circumstances. Women who are pregnant, planning pregnancy, or breastfeeding should discuss their situation with their doctor before starting or continuing this combination medicine.

Storage Instructions

Daplozmet XR 5/500mg tablets should be stored in a cool, dry place away from direct sunlight and excess humidity, at the room temperature indicated on the packaging. Tablets should remain in their original blister pack until they are ready to be used, helping protect them from moisture and light exposure. Keep out of reach of children and pets, and avoid storage in areas with fluctuating temperatures such as bathrooms or vehicles.

FAQS

Q: What does the “XR” in Daplozmet XR mean?
XR refers to the extended-release form of the Metformin component, designed to release gradually over time rather than all at once.

Q: Can Daplozmet XR tablets be split or crushed?
No, the tablet should always be swallowed whole, as splitting or crushing can interfere with its extended-release mechanism.

Q: Is Daplozmet XR taken more than once a day?
It is typically taken once daily, unlike some immediate-release Metformin combinations that may require more frequent dosing, though the exact schedule should follow a doctor’s instructions.

Q: Does the extended-release form reduce stomach-related side effects?
Many patients experience fewer gastrointestinal symptoms with extended-release Metformin compared to immediate-release forms, though individual responses can still vary.

Disclaimer

Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.