Description
Description
Diabold Plus (1/500mg) is a combination oral tablet that brings together Glimepiride and Metformin, two antidiabetic agents that work through different mechanisms to manage type 2 diabetes mellitus. Manufactured by Barrett Hodgson Pakistan, this combination is generally prescribed for patients whose blood sugar isn’t adequately controlled by either medication alone, offering a more comprehensive approach to glycemic management. Each pack contains 30 tablets, produced under strict pharmaceutical quality standards to ensure reliable strength and consistency. By pairing an insulin-stimulating agent with a medication that improves the body’s insulin sensitivity, Diabold Plus provides a dual-action approach to keeping blood glucose levels within a healthier range.
Ingredients
Each Diabold Plus (1/500mg) tablet contains two active ingredients: Glimepiride (1mg) and Metformin (500mg). Glimepiride, a sulfonylurea, works by stimulating the pancreas to release more insulin, while Metformin reduces glucose production in the liver and improves the body’s sensitivity to its own insulin. The tablet also contains standard inactive excipients that support its structure, stability, and consistent absorption, without contributing any therapeutic action themselves.
Dosage Form
Diabold Plus (1/500mg) is available as a film-coated oral tablet, supplied in a strip format totaling 30 tablets per pack. It is intended for oral use, typically taken with meals.
Uses
Diabold Plus (1/500mg) is used for controlling blood sugar levels in patients with type 2 diabetes mellitus who require more than a single medication to achieve adequate glycemic control. By combining two different mechanisms of action, this tablet offers better overall blood sugar management than either Glimepiride or Metformin used on their own. With consistent use as prescribed, it supports the maintenance of normal blood sugar levels, helps prevent organ damage, and lowers the long-term risk of complications involving the heart, kidneys, and brain.
How to Use
Diabold Plus (1/500mg) is generally taken by mouth with a glass of water, right before breakfast or the main meal of the day, to help minimize stomach discomfort and align with the body’s natural response to food. The tablet should be swallowed whole and not crushed or chewed. Taking it at the same time each day helps maintain steady blood sugar control. Any dosage adjustments or changes to the treatment plan should only be made under a doctor’s supervision.
Side Effects
Diabold Plus (1/500mg) may cause side effects linked to its combined mechanism of action. Commonly reported effects include mild hypoglycemia, nausea, stomach upset, or diarrhea, particularly during the initial period of treatment. Some patients may also experience dizziness, headache, or a metallic taste in the mouth. In rare cases, more serious reactions such as lactic acidosis have been reported with Metformin-containing medicines, especially in patients with kidney or liver impairment, and would require immediate medical attention.
Pregnancy & Breastfeeding
Diabold Plus (1/500mg) is generally not recommended during pregnancy, as blood sugar management in pregnant women with diabetes is typically handled with insulin instead. Its safety during breastfeeding has also not been clearly established, so breastfeeding mothers should consult their doctor before using this medication. A healthcare provider will determine the safest approach to blood sugar control during these periods.
Storage Instructions
Store Diabold Plus tablets at room temperature, in a cool, dry place away from direct sunlight and moisture. Keep the tablets in their original packaging until ready for use, and store them safely out of the reach of children. Do not use tablets past their expiry date, and dispose of any unused or expired medicine responsibly.
FAQs
Q1: Why does this tablet combine Glimepiride with Metformin?
Combining the two allows for better blood sugar control by addressing insulin release and insulin sensitivity through two separate mechanisms, which can be more effective than either medicine alone.
Q2: What happens if a dose is missed?
Take it as soon as remembered, but if it’s close to the next meal or dose, skip the missed one rather than doubling up.
Q3: Can this medicine cause low blood sugar?
Yes, particularly due to the Glimepiride component; meals should not be skipped while taking this medication to reduce that risk.
Q4: Is this suitable for patients with kidney issues?
It should be used with caution in such patients, and a doctor should assess kidney function before and during treatment, due to the Metformin component.
Disclaimer
Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.






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