Description

Description

Eskem (40mg) is a higher-strength acid-reducing capsule containing Esomeprazole (as esomeprazole magnesium trihydrate), manufactured by High-Q Pharmaceuticals. Like the 20mg version, it belongs to the proton pump inhibitor (PPI) class of medicines and is generally used for more significant acid-related conditions or when a stronger dose is needed to control symptoms effectively. Esomeprazole works by reducing the secretion of hydrochloric acid in the stomach, altering gastric pH to relieve symptoms and support healing. This strength is often introduced for more severe cases of GERD, ulcers, or other acid-related disorders, once a doctor has assessed the need for stronger acid suppression. The pack contains 14 capsules, generally supporting about two weeks of once-daily treatment as directed by a doctor.

Ingredients

Each Eskem (40mg) capsule contains enteric-coated pellets of Esomeprazole (as esomeprazole magnesium trihydrate) equivalent to 40mg of esomeprazole, along with standard pharmaceutical excipients that support the delayed-release mechanism. The acid-suppressing effect comes entirely from the esomeprazole content.

Dosage Form

This medicine is supplied as an oral capsule containing enteric-coated, acid-labile granules, meant to be swallowed whole with water. It should not be chewed or crushed, since this can disrupt the protective coating designed to shield the medicine from stomach acid.

Uses

Eskem (40mg) is used to treat gastroesophageal reflux disease (GERD), a condition where relaxed muscles above the stomach allow acid to enter the esophagus and cause heartburn and regurgitation. It’s also used, often alongside other medicines, to treat and prevent duodenal and peptic ulcers, and to manage Zollinger-Ellison syndrome, a condition involving excessive stomach acid production. This higher strength is also used to help prevent ulcers caused by NSAIDs or H. pylori infection, typically as part of a combination treatment plan. By blocking the proton pump enzyme system in the stomach lining, this medicine significantly reduces acid secretion, helping relieve symptoms and support healing of the esophagus and stomach lining.

How to Use

Eskem (40mg) is generally taken once daily, before a meal, as directed by a doctor, and the capsule should be swallowed whole with a glass of water rather than crushed or chewed. It’s typically recommended to take it about an hour before eating to allow the medicine to work most effectively. This medicine should be taken consistently and for the full duration recommended by your doctor, particularly when used alongside other medicines to treat ulcers or H. pylori infection. If a dose is missed, it should be taken as soon as remembered, unless it’s close to the time of the next scheduled dose, in which case the missed dose should simply be skipped.

Side Effects

Commonly reported side effects include headache, nausea, diarrhea, abdominal pain, constipation, and flatulence. Dry mouth has also been reported by some patients. With long-term use — generally longer than three years — this medicine may lead to malabsorption or deficiency of vitamin B12 (cyanocobalamin), and prolonged use has also been associated with low magnesium levels and an increased risk of bone fractures. Any severe or persistent side effects, or signs of an allergic reaction, should be reported to a doctor promptly.

Pregnancy & Breastfeeding

Anyone who is pregnant should consult their doctor before taking Eskem (40mg), since the appropriateness of this medicine during pregnancy depends on individual circumstances and should be assessed by a healthcare provider. Similarly, breastfeeding patients should check with their doctor before use, as the safety of esomeprazole in this situation may not be fully established for all cases.

Storage Instructions

Store Eskem (40mg) capsules below 30°C, protected from light and moisture. Keep the capsules in their original packaging until needed, and store them safely out of reach of children. This medicine should only be sold on the prescription of a registered medical practitioner. Any expired or unused capsules should be disposed of properly rather than through household waste.

FAQs

Why is the 40mg strength sometimes used instead of 20mg?
This higher strength is generally used for more severe acid-related conditions or when a doctor determines that stronger acid suppression is needed for adequate symptom control.

Can I take this capsule with food?
It’s generally recommended to take it before a meal, about an hour beforehand, for the best effect, though your doctor’s specific instructions should be followed.

Does long-term use of this medicine carry any particular risks?
Yes, long-term use (typically beyond three years) has been linked to vitamin B12 deficiency, low magnesium levels, and an increased risk of bone fractures, so it’s important to use this medicine as prescribed and have periodic check-ins with your doctor.

Can this medicine be used together with other ulcer treatments?
Yes, it’s often used alongside other medicines, including antibiotics, to treat and prevent ulcers related to H. pylori infection, but this should always be directed by your doctor.

Disclaimer

Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.