Description
Description
Esso-NS 375/20mg is a combination capsule manufactured by Shaigan Pharmaceuticals, containing Naproxen Sodium and Esomeprazole as its active ingredients. Naproxen Sodium is a nonsteroidal anti-inflammatory drug (NSAID) that helps relieve pain, swelling, and inflammation, while Esomeprazole is a proton pump inhibitor (PPI) that reduces stomach acid production to help protect the stomach lining from NSAID-related irritation. This combination is designed to provide pain relief while lowering the risk of stomach ulcers that can occur with long-term NSAID use. Each pack contains 28 capsules. Esso-NS is available only with a valid prescription.
Ingredients
Each Esso-NS capsule contains Naproxen Sodium 375mg and Esomeprazole 20mg as active ingredients, along with standard pharmaceutical excipients that support formulation, stability, and absorption. The formulation follows the quality standards maintained by Shaigan Pharmaceuticals.
Dosage Form
Esso-NS is available as an oral capsule, combining 375mg of Naproxen Sodium and 20mg of Esomeprazole per capsule, supplied in a pack of 28 capsules.
Uses
Esso-NS is prescribed for the relief of signs and symptoms of conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis, particularly in patients who require ongoing NSAID therapy and are at risk of developing stomach ulcers. It combines pain and inflammation relief with a protective effect on the stomach lining. This medicine is generally reserved for patients who need extended NSAID treatment rather than short-term, occasional pain relief. The suitability of this combination should always be determined by a qualified healthcare provider.
How to Use
Esso-NS should be taken exactly as prescribed by your doctor, typically twice daily, at least 30 minutes before a meal. The capsule should be swallowed whole with a glass of water and should not be crushed or chewed, as this may affect how the medicine works. Do not take additional NSAID medicines while using Esso-NS unless specifically advised by your doctor, as this can increase the risk of side effects.
Side Effects
Common side effects of Esso-NS include stomach discomfort, nausea, diarrhea, and headache. Some individuals may experience dizziness or heartburn. NSAIDs like Naproxen carry a risk of gastrointestinal bleeding, cardiovascular effects, and kidney-related changes, particularly with long-term use, so any signs of black or bloody stools, chest pain, or swelling should be reported to a doctor immediately. Long-term PPI use has also been associated with reduced absorption of certain nutrients.
Pregnancy & Breastfeeding
Esso-NS should not be used during pregnancy, particularly in the third trimester, as NSAIDs can cause harm to the unborn baby and affect delivery. Its use during breastfeeding should be discussed with a doctor, as both components may pass into breast milk. Women who are pregnant, planning pregnancy, or breastfeeding should inform their doctor before starting this medication.
Storage Instructions
Store Esso-NS capsules at room temperature, away from direct sunlight, heat, and moisture. Keep the medicine in its original packaging, tightly closed, and out of reach of children. Do not use capsules beyond their printed expiry date.
FAQs
Is Esso-NS available without a prescription?
No, Esso-NS is a prescription-only medicine and should not be used without medical advice.
Why does Esso-NS combine a painkiller with a stomach-protecting medicine?
It provides pain and inflammation relief while reducing the risk of stomach ulcers associated with long-term NSAID use.
How many capsules are in one pack?
Each pack of Esso-NS contains 28 capsules.
Who manufactures Esso-NS?
Esso-NS is manufactured by Shaigan Pharmaceuticals.
Can I take other pain relievers while using Esso-NS?
Not without consulting your doctor, as combining NSAIDs can increase the risk of side effects.
Disclaimer
Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.






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