Description
Description
Flexin (500mg) is an oral medication manufactured by Abbott Laboratories, formulated to help relieve pain, fever, and inflammation in adults who require a higher dose than the standard strength. Each pack contains 20 tablets, with each tablet containing Naproxen, an active substance belonging to a class of medicines known as non-steroidal anti-inflammatory drugs (NSAIDs). This medicine works by inhibiting enzymes in the body responsible for producing prostaglandins, natural substances that trigger pain, swelling, and inflammation. By reducing the production of these substances, Flexin helps ease discomfort and improve mobility in conditions involving inflamed or painful joints and muscles, while also helping to reduce fever when present. This 500mg strength is generally intended for more pronounced pain and inflammation or for individuals who have not achieved adequate relief with the standard 250mg dose. Flexin is intended for use under medical guidance, and the exact treatment plan, including dosage and duration, should always be determined by a qualified physician based on an individual’s specific condition and overall health status.
Ingredients
Each tablet of Flexin (500mg) contains Naproxen 500mg as its active pharmaceutical ingredient, an NSAID that works by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), which are responsible for producing prostaglandins that cause pain, fever, and inflammation in the body. This strength delivers double the active ingredient found in the standard 250mg formulation, distinguishing it as a more concentrated option for stronger symptom relief. The tablet also contains standard pharmaceutical excipients such as binders, fillers, and coating agents, which support the tablet’s physical stability, appearance, and consistent performance without contributing any therapeutic effect of their own.
Dosage Form
Flexin is available as an oral tablet, with each pack containing 20 tablets. The tablet form is designed to deliver a precise, consistent dose of Naproxen with each intake, as directed by a treating physician.
Uses
Flexin (500mg) is primarily used to relieve more pronounced pain and inflammation associated with conditions such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis, as well as acute musculoskeletal disorders including sprains, strains, tendinitis, and bursitis. It may also be used to help manage pain associated with menstrual cramps, headaches, dental pain, and fever. This higher strength is generally considered for individuals whose symptoms have not responded sufficiently to the standard dose, and its longer duration of action compared to some other NSAIDs may allow for less frequent dosing throughout the day, as determined by a treating physician.
How to Use
Flexin should be taken exactly as prescribed by a doctor, typically with food or a full glass of water to help reduce the likelihood of stomach discomfort, particularly given its higher strength. The tablet should be swallowed whole and should not be crushed or chewed unless specifically advised by a healthcare provider. This medicine is generally intended to be used at the lowest effective dose for the shortest duration necessary to manage symptoms, and prolonged use should be monitored by a doctor to reduce the risk of side effects. The maximum recommended daily dose should never be exceeded, and this medicine should not be combined with other NSAIDs without medical advice. If a dose is missed, it should be taken as soon as remembered, unless it is close to the time of the next scheduled dose, in which case the missed dose should be skipped rather than doubled.
Side Effects
Flexin may cause side effects in some individuals, and because this is a higher strength, certain effects may be more pronounced compared to the standard dose. Commonly reported effects include stomach pain, heartburn, nausea, and headache. Less commonly, some individuals may experience dizziness, drowsiness, or skin rash. In rare cases, more serious effects such as gastrointestinal bleeding, ulcers, kidney problems, or allergic reactions can occur, and prolonged use or high doses of NSAIDs such as Naproxen may also increase the risk of cardiovascular events such as heart attack or stroke, particularly in individuals with existing risk factors. Any severe or persistent symptoms, signs of gastrointestinal bleeding such as black stools, chest pain, or an allergic reaction such as facial swelling or difficulty breathing require immediate medical attention. This list is not exhaustive, and a healthcare provider should be consulted for a complete understanding of possible reactions at this strength.
Pregnancy & Breastfeeding
Flexin is generally not recommended during pregnancy, particularly in the third trimester, as NSAIDs such as Naproxen have been associated with risks to fetal development and complications during delivery when used late in pregnancy. Women who are pregnant, planning a pregnancy, or suspect they may be pregnant should inform their doctor immediately so that a suitable alternative for pain management can be considered. Use during breastfeeding should also be discussed with a healthcare provider, as small amounts of the active ingredient may pass into breast milk. Any decision regarding use during pregnancy or lactation should be made only after consultation with a qualified healthcare professional.
Storage Instructions
Flexin tablets should be stored in a cool, dry place away from direct sunlight, excessive heat, and moisture, ideally below 30°C. The tablets should remain in their original packaging until ready for use, and the product should always be kept out of the reach and sight of children and pets. Tablets should not be used beyond their printed expiry date, and any unused or expired medicine should be disposed of responsibly according to local pharmaceutical waste guidelines rather than discarded in regular household trash.
FAQS
How is the 500mg strength different from the 250mg version?
The 500mg strength contains double the active ingredient and is generally intended for more pronounced pain and inflammation or for those who have not achieved adequate relief with the standard dose.
Can Flexin be taken long-term?
It is generally intended for use at the lowest effective dose for the shortest duration necessary, and long-term use should only occur under close medical supervision due to potential gastrointestinal and cardiovascular risks.
Should Flexin be taken with food?
Yes, taking it with food or a full glass of water is generally recommended to help reduce the likelihood of stomach discomfort associated with this medicine, particularly at this higher strength.
Can Flexin be taken alongside other pain relief medicines?
This should only be done under a doctor’s guidance, as combining multiple NSAIDs can increase the risk of side effects, particularly related to the stomach and kidneys.
Disclaimer
Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.






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