Description

Description

Glusimet 50mg/850mg is an oral tablet that combines two active ingredients, Sitagliptin and Metformin Hydrochloride, working together through complementary mechanisms to help control blood sugar in adults with type 2 diabetes. Sitagliptin works by blocking the breakdown of incretins, natural hormones that stimulate insulin production in response to rising blood glucose, while Metformin reduces the amount of glucose produced by the liver, delays intestinal absorption of sugar, and increases the body’s sensitivity to insulin. This particular strength offers a higher Metformin dose within the combination, often used for patients who require more intensive glucose control from that component specifically. The pack contains 14 tablets, typically supplied as two strips of seven, suitable for continued use as part of a broader diabetes management plan.

Ingredients

Each Glusimet 50mg/850mg tablet contains 50mg of Sitagliptin combined with 850mg of Metformin Hydrochloride as its two active ingredients. The tablet also includes standard pharmaceutical excipients such as binders, fillers, and a film coating, which help maintain the tablet’s structure and support consistent absorption once ingested. Patients with known sensitivities to either active ingredient or any of the inactive components should check the packaging or consult a pharmacist before starting treatment.

Dosage Form

Glusimet 50mg/850mg is supplied as a solid, film-coated oral tablet, meant to be swallowed whole with a glass of water, without crushing or chewing.

Uses

Glusimet 50mg/850mg is used for the treatment and control of high blood sugar levels in adults with type 2 diabetes, helping to reduce the risk of complications such as kidney damage, nerve problems, vision issues, and loss of limbs associated with prolonged elevated blood sugar. By combining Sitagliptin’s incretin-based effect with a higher dose of Metformin’s liver-glucose-lowering action, this strength provides more robust blood sugar regulation as an adjunct to diet and exercise.

How to Use

Glusimet 50mg/850mg should be taken exactly as prescribed by a doctor, generally with food to help reduce stomach-related side effects associated with the higher Metformin dose. The tablet should be swallowed whole with a glass of water and should not be crushed or chewed. Diet and exercise should be maintained alongside this medicine for the best and most consistent results, and treatment should be continued at the same time each day unless a doctor advises otherwise. If a dose is missed, it should be taken as soon as remembered, unless it is close to the time of the next scheduled dose.

Side Effects

Common side effects of Glusimet 50mg/850mg include diarrhea, nausea, vomiting, abdominal discomfort, headache, and loss of appetite, which may be more noticeable at this higher Metformin strength, particularly when treatment is first started. Some patients may also experience hypoglycemia, especially if combined with other antidiabetic medicines, alcohol, or a skipped meal. Less commonly, more serious effects can occur, such as signs of lactic acidosis, a rare but serious condition associated with Metformin, or pancreatitis. Any unusual symptoms, including severe abdominal pain, muscle pain, breathing difficulty, or severe fatigue, should be reported to a doctor immediately.

Pregnancy & Breastfeeding

Glusimet 50mg/850mg is generally not recommended during pregnancy, as the safety of the Sitagliptin component for a developing baby has not been fully established, even though Metformin is sometimes used during pregnancy under close medical supervision. Its use during breastfeeding is also generally discouraged due to limited safety data on the combined formulation. Women who are pregnant, planning to conceive, or breastfeeding should consult their doctor before starting this medicine.

Storage Instructions

Glusimet 50mg/850mg tablets should be stored at room temperature, in a dry place away from direct sunlight and excess heat. The tablets should be kept in their original packaging until needed and stored well out of the reach of children and pets. Tablets should not be used past their expiry date, and any expired or unused tablets should be disposed of properly.

FAQs

Why might a doctor prescribe the 850mg Metformin strength instead of 500mg?
The higher Metformin dose is generally used when a patient requires more intensive glucose-lowering support from that component specifically, based on their overall treatment response.

Why is Glusimet 50mg/850mg often taken with food?
Taking it with food helps reduce the stomach-related side effects, such as nausea or diarrhea, that are commonly associated with the Metformin component, especially at this higher strength.

Can Glusimet 50mg/850mg cause low blood sugar on its own?
It is not typically associated with hypoglycemia when used alone, but the risk increases when combined with other antidiabetic medicines, alcohol, or skipped meals.

Should I continue diet and exercise while taking Glusimet 50mg/850mg?
Yes, maintaining a proper diet and exercise routine alongside this medicine is important for the best and most consistent blood sugar control.

Disclaimer

Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.