Description

Description

Inosita Plus 50/1000mg is a prescription combination tablet manufactured by PharmEvo, bringing together Sitagliptin and Metformin in a single dose for the management of type 2 diabetes mellitus. Sitagliptin belongs to the DPP-4 inhibitor class and works by supporting the body’s natural incretin hormone activity, while Metformin belongs to the biguanide class and works mainly by reducing the amount of glucose released by the liver while improving how effectively the body responds to insulin. This is the highest available strength in the Inosita Plus range, generally reserved for patients who need the maximum recommended Metformin component alongside their Sitagliptin therapy. Each pack contains 28 tablets, offering a convenient supply for ongoing, doctor-supervised diabetes management.

Ingredients

Each film-coated tablet of Inosita Plus 50/1000mg contains two active pharmaceutical ingredients: 50 milligrams of Sitagliptin, present as its phosphate monohydrate form, and 1000 milligrams of Metformin hydrochloride. The film coating makes the tablet easier to swallow and offers some protection to the active ingredients during their passage through the stomach before absorption. In addition to the active substances, the tablet contains standard inactive ingredients such as binders and coating agents, included solely to support the tablet’s structure, texture, and shelf stability.

Dosage Form

Inosita Plus 50/1000mg is supplied as an oral, film-coated combination tablet. Being a solid dosage form, it should be swallowed whole with water and should not be crushed, chewed, or split, since altering the tablet could interfere with how evenly the two active ingredients are released and absorbed in the body.

Uses

Inosita Plus 50/1000mg is used to help manage blood glucose levels in adults with type 2 diabetes mellitus, particularly when treatment with a single anti-diabetic agent or a lower-strength combination has not achieved sufficient blood sugar control. Sitagliptin helps raise natural incretin hormone levels that stimulate insulin release in response to elevated blood sugar and reduce glucagon secretion, while Metformin works to lower excess glucose production in the liver and improve how effectively the body’s tissues use insulin. Together, this higher-strength combination is intended to provide more comprehensive glycemic control for patients with greater treatment needs, and it is typically used alongside a controlled diet and regular physical activity as part of an overall diabetes care plan.

How to Use

Inosita Plus 50/1000mg is generally taken with meals, as directed by the prescribing doctor, since taking it with food can help reduce the digestive side effects sometimes associated with the Metformin component. Because this is the maximum available strength, the dosing schedule prescribed by the doctor should be followed carefully and should not be exceeded. The tablet should be swallowed whole with a glass of water rather than chewed or crushed. Patients should not adjust their dose or discontinue the medicine without medical advice, and regular blood sugar monitoring along with periodic kidney and liver function checks is generally recommended throughout treatment, particularly given the higher Metformin content.

Side Effects

The most commonly reported side effects of Inosita Plus 50/1000mg involve the digestive system, including nausea, mild stomach upset, diarrhea, or reduced appetite, particularly when treatment is first started or the dose is increased. Some patients may also notice headache or mild dizziness. Because this tablet contains the highest available dose of Metformin in the Inosita Plus range, there is a rare but serious risk of lactic acidosis, especially in individuals with kidney problems, liver impairment, dehydration, or heavy alcohol use; warning signs can include unusual tiredness, muscle pain, difficulty breathing, or stomach discomfort, and this situation requires urgent medical attention. As with other Sitagliptin-containing medicines, there is also a small possibility of low blood sugar when this combination is used together with certain other diabetes treatments, along with rare reports of pancreatitis or allergic reactions.

Pregnancy & Breastfeeding

There is limited established safety information regarding the use of this Sitagliptin and Metformin combination during pregnancy or while breastfeeding. Inosita Plus 50/1000mg should therefore only be used in these situations if a doctor determines that the potential benefit outweighs any possible risk to the mother or baby. Women who are pregnant, planning to become pregnant, or currently breastfeeding should discuss appropriate diabetes management options with their healthcare provider before starting or continuing this medication.

Storage Instructions

Inosita Plus tablets should be stored at room temperature, generally below 30°C, in a dry place away from direct sunlight, excess heat, and moisture. Keeping the tablets in their original blister packaging until they are needed helps protect them from humidity. The medicine should always be kept out of the reach of children and pets, and any expired or unused tablets should be disposed of properly rather than kept for later use.

FAQs

Is 50/1000mg the strongest version of Inosita Plus?
Yes, this strength contains the maximum Metformin dose available in the Inosita Plus range, combined with the standard 50mg Sitagliptin dose.

Should Inosita Plus 50/1000mg be taken with food?
Yes, taking it with meals is generally recommended to help reduce stomach-related side effects associated with the higher Metformin content.

Is this strength suitable for people with kidney problems?
This depends heavily on the degree of kidney impairment, since the higher Metformin dose increases the importance of monitoring kidney function; a doctor must assess this carefully before and during treatment.

Can Inosita Plus 50/1000mg be used for type 1 diabetes?
No, it is intended specifically for type 2 diabetes mellitus and is not appropriate for type 1 diabetes or diabetic ketoacidosis.

Disclaimer

Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.