Description

Description

ITP OD (150mg) is a prescription gastroprokinetic medicine manufactured by Sami Pharmaceuticals, formulated with Itopride Hydrochloride in an extended-release tablet designed for convenient once-daily dosing. It belongs to the same class of medicines as the standard-release ITP tablet, working through a dual mechanism as a dopamine D2 receptor antagonist and an acetylcholinesterase inhibitor. By activating gastrointestinal propulsive motility through these combined actions, Itopride helps food and stomach contents move more efficiently through the digestive tract, easing symptoms of bloating, indigestion, and delayed stomach emptying. Itopride works by promoting the release of acetylcholine while inhibiting its breakdown, which stimulates spontaneous propulsive contractions in the stomach and speeds up gastric emptying. The extended-release formulation delivers this effect gradually over the day, offering sustained symptom relief with a single daily tablet rather than the multiple daily doses required with the standard-release version. This once-daily convenience makes ITP OD particularly suited to individuals managing chronic or recurring motility-related digestive complaints. Each pack of ITP OD (150mg) contains 10 tablets.

Ingredients

Each ITP OD tablet contains Itopride Hydrochloride at a strength of 150 milligrams in extended-release form. The tablet also contains standard pharmaceutical excipients that support its sustained-release mechanism and film coating. Individuals with a known allergy to Itopride or to any inactive ingredient should avoid this medicine and should review the enclosed leaflet or consult a pharmacist regarding other known sensitivities.

Dosage Form

ITP OD (150mg) is supplied as an oral, extended-release, film-coated tablet intended to be swallowed whole with a glass of water. It should not be crushed or chewed, as doing so would disrupt the sustained-release mechanism responsible for its once-daily action. Tablets are packaged within protective blister strips inside an outer carton, with this pack containing a total of 10 tablets.

Uses

ITP OD (150mg) is used to relieve symptoms associated with reduced gastrointestinal motility, including functional dyspepsia, bloating, upper abdominal discomfort, regurgitation, heartburn, nausea, and vomiting. It is also used to manage gastroesophageal reflux disease (GERD) and gastroparesis (delayed gastric emptying). Its extended-release, once-daily formulation makes it particularly convenient for individuals with chronic digestive motility issues who prefer a simplified dosing schedule compared to multiple daily doses.

How To Use

ITP OD is typically taken as one tablet once daily, preferably before a meal, or as specifically directed by a healthcare provider. The tablet should be swallowed whole with a glass of water and should never be crushed or chewed, as this would interfere with its sustained-release action. If a dose is missed, it should be taken as soon as remembered, unless it is close to the time of the next scheduled dose, in which case the missed dose should be skipped rather than doubled. Consistent daily use, exactly as prescribed, helps maintain steady symptom control.

Side Effects

Commonly reported side effects of ITP OD include diarrhea, constipation, abdominal pain, headache, dizziness, nausea, and increased salivation or dry mouth. Less commonly, fatigue, drowsiness, or skin reactions such as rash, redness, or itching have been reported. Rare but more significant effects include changes in blood cell counts, increased prolactin levels leading to breast tenderness or enlargement, and liver-related changes such as jaundice. This medicine should not be used in patients with a known bowel obstruction, internal bleeding, or perforation, and should be used with particular caution in elderly patients and those with liver or kidney impairment, given an increased risk of side effects in these groups.

Pregnancy & Breastfeeding

ITP OD should be avoided during pregnancy and breastfeeding unless specifically prescribed by a doctor, as safety data for this period is limited. Women who are pregnant, planning pregnancy, or breastfeeding should consult their healthcare provider before starting this medicine to weigh the potential benefits against any unknown risks. If use is considered absolutely necessary while breastfeeding, a doctor may advise discontinuing breastfeeding during treatment.

Storage Instructions

ITP OD tablets should be stored in a cool, dry place, protected from direct sunlight, excess heat, and humidity, as improper storage may affect the medicine’s stability. Tablets should remain in their original blister packaging until needed, and the medicine should be stored securely out of reach and sight of children.

FAQs

How is ITP OD different from the standard 50mg ITP tablet?
ITP OD is an extended-release formulation taken once daily, while the standard tablet is taken multiple times a day — both use the same active ingredient, Itopride Hydrochloride.
Can the tablet be crushed if swallowing is difficult?
No, it should always be swallowed whole, as crushing or chewing disrupts its sustained-release mechanism.
Is ITP OD safe for elderly patients?
It should be used with caution in elderly patients, as the risk of side effects is increased in this group — close medical supervision is recommended.
What should I do if I notice signs of intestinal blockage?
Symptoms like severe bloating, vomiting, or severe abdominal cramps should be reported to a doctor immediately, as this medicine is not recommended in cases of bowel obstruction.

Disclaimer

Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.