Description

Description

Jentin-Met is an oral tablet that combines two active ingredients, Sitagliptin and Metformin Hydrochloride, working together through complementary mechanisms to help control blood sugar in adults with type 2 diabetes. Sitagliptin, a DPP-4 inhibitor, increases and prolongs the activity of natural hormones called incretins, boosting insulin release and reducing glucagon levels in a glucose-dependent manner, while Metformin, a biguanide, lowers both fasting and after-meal blood glucose by reducing liver glucose production and improving insulin sensitivity. This dual-action combination provides more comprehensive blood sugar control for patients who require more than a single medicine alone. The pack contains 14 tablets, suitable for continued daily use as part of a broader diabetes management plan.

Ingredients

Each Jentin-Met tablet contains Sitagliptin Phosphate Monohydrate equivalent to 50mg of Sitagliptin, combined with 500mg of Metformin Hydrochloride as its two active ingredients. The tablet also includes standard pharmaceutical excipients such as binders, fillers, and a film coating, which help maintain the tablet’s structure and support consistent absorption once ingested. Patients with known sensitivities to either active ingredient or any of the inactive components should check the packaging or consult a pharmacist before starting treatment.

Dosage Form

Jentin-Met is supplied as a solid, film-coated oral tablet, meant to be swallowed whole with a glass of water, without crushing, breaking, or chewing.

Uses

Jentin-Met is indicated as an adjunct to diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus, particularly when a single-ingredient treatment has not achieved adequate glucose management. By combining Sitagliptin’s incretin-based effect with Metformin’s ability to reduce liver glucose production, this combination helps regulate both fasting and after-meal blood sugar levels. It is not intended for use in patients with type 1 diabetes or for treating diabetic ketoacidosis.

How to Use

Jentin-Met should be taken exactly as prescribed by a doctor, generally with meals to help reduce stomach-related side effects associated with the Metformin component. The tablet should be swallowed whole with a glass of water and should not be crushed, broken, or chewed. The dosage should be adjusted based on self-monitoring of blood glucose levels and the individual’s clinical response, with the maximum recommended Sitagliptin dose generally not exceeding 100mg per day. Alongside this medicine, patients are generally encouraged to maintain a healthy diet and regular exercise routine. If a dose is missed, it should be taken as soon as remembered, unless it is close to the time of the next scheduled dose.

Side Effects

Common side effects of Jentin-Met include nausea, upper abdominal pain, and a decrease in blood glucose levels. Some patients may also experience diarrhea or drowsiness, particularly when treatment is first started or the dose is increased. Less commonly, more serious effects can occur, such as signs of lactic acidosis, a rare but serious condition associated with Metformin, or pancreatitis. Any unusual symptoms, including severe abdominal pain, muscle pain, breathing difficulty, or severe fatigue, should be reported to a doctor immediately.

Pregnancy & Breastfeeding

Jentin-Met is generally not recommended during pregnancy, as the safety of the Sitagliptin component for a developing baby has not been fully established, even though Metformin is sometimes used during pregnancy under close medical supervision. Its use during breastfeeding is also generally discouraged due to limited safety data on the combined formulation. Women who are pregnant, planning to conceive, or breastfeeding should consult their doctor before starting this medicine.

Storage Instructions

Jentin-Met tablets should be stored at room temperature, in a dry place away from direct sunlight and excess heat. The tablets should be kept in their original packaging until needed and stored well out of the reach of children and pets. Tablets should not be used past their expiry date, and any expired or unused tablets should be disposed of properly.

FAQs

Does Jentin-Met cause low blood sugar on its own?
Metformin does not typically cause hypoglycemia by itself, but the combination may lower blood glucose when taken alongside other diabetes medicines; report any symptoms of low blood sugar to your doctor.

Why is Jentin-Met often taken with meals?
Taking it with food helps reduce the stomach-related side effects, such as nausea or diarrhea, that are commonly associated with the Metformin component.

Can Jentin-Met be used by patients with type 1 diabetes?
No, it is intended specifically for type 2 diabetes and is contraindicated in patients with diabetic ketoacidosis.

What is the maximum recommended dose of Sitagliptin within this combination?
The maximum recommended dose is generally 100mg of Sitagliptin per day, adjusted based on blood glucose monitoring and clinical response.

Disclaimer

Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.