Description

Description

Linjardy 5/25mg is a fixed-dose combination tablet that pairs a standard dose of Linagliptin with the highest available strength of Empagliflozin, packaged 14 tablets to a pack. Linagliptin, a DPP-4 inhibitor, helps the pancreas release more insulin around mealtimes while also reducing the liver’s glucose output, while Empagliflozin, an SGLT2 inhibitor, works through a separate route by prompting the kidneys to clear excess glucose through urine. This particular strength is generally reserved for patients who need a stronger SGLT2 effect than the 10mg version provides, while keeping the Linagliptin dose steady, allowing the two complementary mechanisms to work together in a single once-daily tablet.

Ingredients

Each Linjardy 5/25mg tablet contains:

• Linagliptin – 5 mg
• Empagliflozin – 25 mg

The tablet also contains standard inactive excipients and a film coating, present only to support the tablet’s structure and ease of swallowing, without any therapeutic effect of their own.

Dosage Form

Linjardy 5/25mg is manufactured as a film-coated oral tablet, supplied 14 tablets per pack, taken by mouth once daily as directed by a physician.

Uses

Linjardy 5/25mg is generally prescribed to:

• Improve blood glucose control in adults with type 2 diabetes mellitus who need a stronger SGLT2 inhibitor component alongside Linagliptin
• Continue combination therapy for patients already stabilized on Linagliptin and Empagliflozin 25mg taken as separate tablets
• Support broader diabetes management, including potential cardiovascular benefits associated with higher Empagliflozin exposure, when paired with an appropriate diet and consistent physical activity

It is not intended for people with type 1 diabetes or for the management of diabetic ketoacidosis.

How to Use

The following points are general guidance only — always follow the specific instructions given by your prescribing doctor:

• Take one tablet by mouth once daily, generally in the morning, with or without food.
• Try to take the dose at the same time each day to help maintain steady blood sugar control.
• Swallow the tablet whole with a glass of water; do not crush or chew it unless specifically advised otherwise.
• Continue regular blood sugar monitoring as instructed by your healthcare provider, since medication works alongside, not instead of, lifestyle management.
• If a dose is missed, take it as soon as remembered unless it is almost time for the next dose, in which case skip the missed one rather than doubling up.

Side Effects

Some patients tolerate Linjardy 5/25mg well, while others may notice side effects such as:

• Increased urination, which may be more noticeable at this higher Empagliflozin dose
• Mild dehydration or increased thirst
• Urinary tract or genital yeast infections
• Upper respiratory symptoms such as a runny or stuffy nose
• Mild digestive discomfort, including nausea or diarrhea

Less commonly, more serious effects can occur, including a marked drop in blood pressure, signs of pancreatitis such as persistent abdominal pain, or symptoms suggesting diabetic ketoacidosis such as ongoing nausea, vomiting, or abdominal discomfort even when blood sugar readings appear normal. Joint pain has also been reported in some patients taking DPP-4 inhibitors like Linagliptin. Any of these symptoms should prompt medical attention. This list is not exhaustive, so any unusual or persistent symptom should be discussed with a doctor or pharmacist.

Pregnancy & Breastfeeding

Linjardy 5/25mg is generally not recommended during pregnancy, particularly from the second trimester onward, as the Empagliflozin component may affect fetal kidney development. It is also not typically advised while breastfeeding, since safety data for both components in this setting is limited. Women who are pregnant, planning to become pregnant, or currently breastfeeding should inform their doctor before starting this medication, so that a more suitable alternative treatment can be considered if needed.

Storage Instructions

• Store Linjardy 5/25mg tablets at room temperature, ideally below 25°C, away from direct sunlight, heat, and humidity.
• Keep tablets in their original blister packaging until they are ready to be used.
• Store out of reach of children.
• Do not use tablets past their printed expiry date, and dispose of unused medicine responsibly rather than through household waste.

FAQS

How does the 5/25mg strength differ from the 5/10mg version?
Both contain the same Linagliptin dose, but this version has the highest available Empagliflozin strength, generally chosen when stronger SGLT2 inhibition is needed for adequate glycemic control.

Will I notice more urination on this strength?
Some patients experience a more pronounced increase in urinary frequency due to the higher Empagliflozin dose, which is generally expected and manageable with adequate fluid intake.

Can Linjardy 5/25mg cause low blood sugar on its own?
Used alone, the risk of hypoglycemia is relatively low, but it increases when combined with insulin or sulfonylurea medications, so your doctor will monitor this closely if you’re on multiple treatments.

Is closer monitoring needed at this Empagliflozin strength?
Yes, your doctor may recommend more frequent monitoring of kidney function and hydration status, particularly when starting or adjusting to this dose.

Can I switch directly from 5/10mg to 5/25mg on my own?
No, any change in dosage strength should only be made under a doctor’s guidance, based on your blood sugar response and overall tolerance.

Disclaimer

Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.