Description
Description
Metliptin is a combination medicine manufactured by Tabros Pharma, containing two active ingredients — Sitagliptin (50mg) and Metformin (850mg) — packed in a strip of 28 tablets. This medicine brings together two different classes of blood sugar-lowering agents in a single tablet, and this strength contains a higher dose of Metformin, generally used for patients who need a stronger effect on blood sugar than the lower-dose combination provides. By combining a medicine that enhances the body’s own insulin response with one that improves how the body uses insulin, Metliptin offers a more comprehensive approach to blood sugar management. It is intended for adult patients under the supervision of a registered physician and is not meant for self-diagnosis or self-medication.
Ingredients
Each tablet of Metliptin contains Sitagliptin 50mg, a DPP-4 inhibitor that works by increasing the levels of certain natural hormones in the body that help the pancreas release insulin when blood sugar is high, along with Metformin 850mg, which works by reducing the amount of sugar produced by the liver and improving the body’s sensitivity to insulin in muscle and fat tissue. Together, these two ingredients approach blood sugar control from separate angles, with the higher Metformin dose in this combination generally providing a more pronounced effect on blood sugar than the lower-strength option.
Dosage Form
Metliptin is available as an oral tablet. Each pack contains 28 tablets, arranged in a blister strip for convenient storage and use. The tablets are meant to be swallowed whole and should not be crushed or chewed unless a healthcare provider has specifically advised otherwise.
Uses
Metliptin is primarily used to help control blood sugar levels in adults with type 2 diabetes, particularly in those who need a stronger Metformin dose than the lower combination strength provides or who have not achieved adequate control with Metformin alone. It works alongside a suitable diet and exercise plan to help bring blood sugar within a target range and reduce the long-term complications associated with poorly controlled diabetes. This medicine does not cure diabetes; it helps manage blood sugar levels as long as it is taken consistently and combined with appropriate lifestyle measures as advised by a doctor.
How to Use
Metliptin should only be taken exactly as prescribed by a doctor. It is generally taken with meals, which helps reduce the likelihood of stomach upset associated with the Metformin component, and the frequency of dosing is determined by the doctor based on individual blood sugar control needs. Doses should not be skipped or stopped abruptly, even if blood sugar levels appear to have improved, unless a doctor advises otherwise. If a dose is missed, it should be taken as soon as remembered with food, but skipped if it is almost time for the next dose, without doubling up. Given the higher Metformin strength in this combination, the dose should never be altered independently, as adjustments are typically based on blood sugar monitoring and overall treatment goals set by the prescribing doctor.
Side Effects
As with most medicines, Metliptin may cause side effects in some individuals, and gastrointestinal effects in particular may be somewhat more noticeable at this higher Metformin strength. Commonly reported effects include nausea, diarrhea, stomach discomfort, and a reduced appetite, particularly when treatment is first started. Some patients may also experience headache or mild upper respiratory symptoms. Less commonly, more serious effects such as inflammation of the pancreas, indicated by persistent and severe abdominal pain, or a rare but serious condition involving a buildup of lactic acid in the body, may occur, and these would require immediate medical attention. Any signs of an allergic reaction, including rash, swelling, or difficulty breathing, should also be treated as a medical emergency.
Pregnancy & Breastfeeding
Metliptin is generally not recommended during pregnancy, as blood sugar control in pregnancy is typically managed with insulin rather than oral medicines, and the safety of this combination for the developing baby has not been firmly established. Women who are pregnant, planning a pregnancy, or suspect they may be pregnant should inform their doctor immediately, as their treatment plan will likely need to be adjusted. It is also generally advised to avoid this medicine while breastfeeding, since it is not clearly established how it may affect a nursing infant. A doctor should always be consulted to discuss safe alternatives during these periods.
Storage Instructions
Metliptin should be stored in a cool, dry place away from direct sunlight and moisture, and kept in its original blister pack until ready for use. It is best stored at room temperature, generally below 30°C, unless otherwise indicated on the packaging, and should be kept out of reach of children and pets. The medicine should not be used beyond its printed expiry date, and expired or unused tablets should be disposed of responsibly.
FAQs
How is this strength different from the 50/500mg combination?
This version contains a higher dose of Metformin, offering a stronger effect on blood sugar while keeping the same amount of Sitagliptin, and is typically prescribed when the lower-dose combination has not achieved the desired control.
Should Metliptin be taken with food?
Yes, taking it with meals is generally recommended, as this can help reduce stomach-related side effects associated with the Metformin component, particularly at this higher strength.
What should I do if I experience persistent stomach upset?
Mild stomach discomfort is common when starting treatment, but persistent or severe symptoms should be reported to a doctor, as the dose or treatment plan may need to be reviewed.
Do I need regular monitoring while taking this medicine?
Yes, regular blood sugar monitoring, along with periodic checks of kidney function, is typically recommended throughout treatment.
Can I stop taking Metliptin once my blood sugar improves?
No, this medicine should not be discontinued without medical advice, as ongoing treatment combined with lifestyle measures is usually needed to maintain blood sugar control.
Disclaimer
Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.






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