Description
Description
Neoglip XR 50/500mg is an extended-release combination tablet manufactured by ATCO Laboratories, containing Sitagliptin and Metformin HCl as its active ingredients. Sitagliptin belongs to a class of medicines called DPP-4 inhibitors that help increase insulin release after meals, while Metformin HCl works by reducing the amount of sugar produced by the liver and improving the body’s response to insulin. The extended-release (XR) formulation allows the medicine to be released gradually into the body, supporting more stable blood sugar control with a simplified dosing routine. Each pack contains 14 tablets. Neoglip XR is available only with a valid prescription and should be used under proper medical supervision.
Ingredients
Each Neoglip XR tablet contains Sitagliptin 50mg and Metformin HCl 500mg as active ingredients, formulated in an extended-release base, along with standard pharmaceutical excipients that support controlled release, stability, and absorption. The formulation follows the quality standards maintained by ATCO Laboratories.
Dosage Form
Neoglip XR is available as an oral extended-release tablet, combining 50mg of Sitagliptin and 500mg of Metformin HCl per tablet, supplied in a pack of 14 tablets.
Uses
Neoglip XR is prescribed for the management of type 2 diabetes in adults, typically when blood sugar is not adequately controlled by diet, exercise, and a single medication alone. The extended-release formulation is often selected for patients who benefit from a more gradual release profile or who experience digestive discomfort with immediate-release Metformin. This medicine is not intended for type 1 diabetes or diabetic ketoacidosis. Its suitability for a particular patient should always be determined by a qualified healthcare provider.
How to Use
Neoglip XR should be taken exactly as prescribed by your doctor, usually once daily with the evening meal. The tablet must be swallowed whole with a glass of water; it should never be crushed, split, or chewed, as this can interfere with the extended-release mechanism. Blood sugar levels should be monitored regularly during treatment, and the dose should not be adjusted without medical guidance.
Side Effects
Common side effects of Neoglip XR include nausea, diarrhea, stomach discomfort, and reduced appetite, particularly during the initial period of treatment. Some individuals may notice the tablet shell in their stool, which is a normal part of the extended-release process and not a cause for concern. Less commonly, this medicine may contribute to a rare but serious condition called lactic acidosis, especially in individuals with kidney or liver problems; symptoms such as unusual muscle pain, difficulty breathing, or extreme tiredness should be reported to a doctor immediately. Low blood sugar may occur, particularly if combined with other diabetes medicines.
Pregnancy & Breastfeeding
Neoglip XR should only be used during pregnancy or breastfeeding if specifically advised by a doctor, as diabetes management needs often change during these periods and alternative treatments may be preferred. Women who are pregnant, planning pregnancy, or breastfeeding should discuss their treatment plan with their healthcare provider.
Storage Instructions
Store Neoglip XR tablets at room temperature, away from direct sunlight, heat, and moisture. Keep the medicine in its original packaging, tightly closed, and out of reach of children. Do not use tablets beyond their printed expiry date.
FAQs
How is Neoglip XR different from regular Neoglip? Neoglip XR is an extended-release formulation designed to release the medicine gradually, often allowing once-daily dosing with fewer digestive side effects.
Can I crush or split Neoglip XR tablets? No, the tablet must be swallowed whole to preserve its extended-release effect.
How many tablets are in one pack? Each pack of Neoglip XR contains 14 tablets.
Who manufactures Neoglip XR? Neoglip XR is manufactured by ATCO Laboratories.
Is it normal to notice something in my stool after taking this medicine? Yes, seeing the empty tablet shell in the stool is a normal and expected part of the extended-release process.
Disclaimer
Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.






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