Description
Description
Izato (500mg) is a prescription antiparasitic medicine manufactured by Sami Pharmaceuticals, formulated with Nitazoxanide as its active ingredient. It belongs to a broad-spectrum class of medicines effective against a range of intestinal parasites, certain bacteria, and select viral infections. Nitazoxanide works by interfering with the essential energy metabolism processes that parasites and other microorganisms rely on to survive and reproduce, disrupting the production of nucleic acids necessary for their growth. This mechanism of action gives Nitazoxanide activity against protozoal parasites such as Giardia lamblia and Cryptosporidium parvum, common causes of persistent infectious diarrhea, as well as certain bacteria including Salmonella and Listeria. Beyond its antiparasitic and antibacterial properties, Nitazoxanide has also demonstrated antiviral activity, and has been studied for viral illnesses including chronic hepatitis C and, in some contexts, other viral gastroenteritis-causing pathogens. Izato is generally used as a short, targeted treatment course rather than for ongoing use, aimed at clearing the specific infection responsible for a patient’s symptoms. Each pack of Izato (500mg) contains 20 tablets.
Ingredients
Each Izato tablet contains Nitazoxanide at a strength of 500 milligrams. The tablet also contains standard pharmaceutical excipients that support its shape, stability, and breakdown once ingested. Individuals with a known allergy to Nitazoxanide or to any inactive ingredient should avoid this medicine and should review the enclosed leaflet or consult a pharmacist regarding other known sensitivities.
Dosage Form
Izato (500mg) is supplied as an oral tablet intended to be swallowed with a glass of water, generally taken with food. Tablets are packaged within protective blister strips inside an outer carton, with this pack containing a total of 20 tablets.
Uses
Izato (500mg) is primarily used for the treatment of diarrhea caused by the intestinal parasites Giardia lamblia and Cryptosporidium parvum in adults and children. It may also be used for certain other protozoal infections, including those caused by Entamoeba histolytica, and has activity against select bacteria such as Salmonella and Listeria. In some treatment settings, it is used for viral gastroenteritis, and its broader antiviral properties have also been explored for conditions such as chronic hepatitis C, though such uses should be guided specifically by a physician based on the diagnosis.
How To Use
Izato tablets are typically taken with food, following the specific dosing schedule set by the prescribing physician, since treatment duration and frequency depend on the particular infection being treated. It is important to complete the full prescribed course, even if symptoms improve before the course is finished, to help ensure the infection is fully cleared and to reduce the likelihood of it returning. If a dose is missed, it should be taken as soon as remembered, unless it is nearly time for the next scheduled dose, in which case the missed dose should be skipped.
Side Effects
Izato is generally well tolerated, though some individuals may experience mild gastrointestinal discomfort, headache, abdominal pain, or nausea. Because it can affect the liver, kidneys, or pancreas at higher-than-recommended doses, an overdose may lead to allergic reactions, elevated liver enzymes, or more pronounced nausea, and should be treated as a medical concern requiring prompt attention. Any unusual or persistent symptoms should be discussed with a doctor, and the prescribed dosage should not be exceeded to ensure both safety and effectiveness.
Pregnancy & Breastfeeding
The use of Izato during pregnancy should only be considered if a doctor determines it is clearly necessary, weighing the potential benefits against any unknown risks, as with many antiparasitic medicines used during this period. Women who are pregnant or planning pregnancy should inform their doctor before starting treatment. Regarding breastfeeding, a doctor should be consulted before use, as safety data during this period is limited, and any decision should be made together with a healthcare provider based on the specific infection being treated.
Storage Instructions
Izato tablets should be stored at room temperature, protected from direct sunlight, excess heat, and moisture. Tablets should remain in their original blister packaging until needed, and the medicine should be stored securely out of reach and sight of children.
FAQs
What infections does Izato commonly treat?
It is mainly used for diarrhea caused by parasites such as Giardia lamblia and Cryptosporidium parvum, and may also address certain bacterial and viral infections as directed by a doctor.
Is Izato suitable for children?
It can be used in children, though those under 12 years should only use it under a doctor’s specific guidance and supervision.
Should the full course be completed even if symptoms improve?
Yes, completing the full prescribed course helps ensure the infection is fully cleared and reduces the risk of it returning.
What happens with an overdose?
An overdose may affect the liver, kidneys, or pancreas and can cause allergic reactions or elevated liver enzymes — this requires prompt medical attention.
Disclaimer
Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.






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