Description
Description
Jardy-Met 12.5/1000mg is a fixed-dose combination tablet that pairs the highest available strength of Empagliflozin with the maximum single-tablet dose of Metformin in this range, packaged 14 tablets to a pack. Empagliflozin, an SGLT2 inhibitor, works by prompting the kidneys to release excess glucose through urine, while Metformin lowers blood sugar mainly by reducing the liver’s glucose output and improving the body’s sensitivity to its own insulin. This particular combination is generally reserved for patients who are already established on both components at their higher individual doses and need the strongest available version of this fixed-dose tablet to maintain effective glycemic control.
Ingredients
Each Jardy-Met 12.5/1000mg tablet contains:
- Empagliflozin – 12.5 mg
- Metformin Hydrochloride – 1000 mg
The tablet also contains standard inactive excipients and a film coating, present only to support the tablet’s structure and ease of swallowing, with no therapeutic action of their own.
Dosage Form
Jardy-Met 12.5/1000mg is manufactured as a film-coated oral tablet, supplied 14 tablets per pack, taken by mouth as directed by a physician.
Uses
Jardy-Met 12.5/1000mg is generally prescribed to:
- Improve blood glucose control in adults with type 2 diabetes mellitus who require the highest combined strength of Empagliflozin and metformin available in this fixed-dose tablet
- Continue combination therapy for patients already stabilized on Empagliflozin 12.5mg and metformin 1000mg taken as separate tablets
- Support broader long-term diabetes management, including potential cardiovascular and kidney-related benefits, when paired with an appropriate diet and consistent physical activity
It is not intended for people with type 1 diabetes or for the management of diabetic ketoacidosis.
How to Use
The following points are general guidance only — always follow the exact instructions given by your prescribing doctor:
- Take the tablet with meals, which helps reduce the digestive side effects commonly linked to higher doses of metformin.
- Your doctor will set the dosing schedule based on your blood sugar control, kidney function, and overall tolerance to both components.
- Swallow the tablet whole with a glass of water; do not crush or chew it, as this can affect absorption.
- Keep to a consistent daily schedule to help support stable blood sugar management.
- Attend scheduled blood tests, including kidney function monitoring, since safe use at this maximum strength depends heavily on adequate kidney health.
Side Effects
Side effects can vary between individuals, but commonly reported ones include:
- Nausea, diarrhea, or general stomach discomfort, particularly during the first few weeks of treatment or after a dose increase
- Reduced appetite or a metallic taste in the mouth
- Increased urinary frequency, often more noticeable at this higher Empagliflozin dose
- Mild dehydration or increased thirst
- Urinary tract or genital yeast infections
Less commonly, more serious concerns can occur, including a marked drop in blood pressure, lactic acidosis (a rare but serious risk tied to metformin, more likely with reduced kidney or liver function, and one that carries a somewhat higher relevance at this maximum metformin strength), or symptoms suggesting diabetic ketoacidosis such as persistent nausea, vomiting, or abdominal pain even when blood sugar readings appear normal. Any of these symptoms require urgent medical attention. This overview is not exhaustive, so any unusual or persistent symptom should be reported to a doctor or pharmacist.
Pregnancy & Breastfeeding
Jardy-Met 12.5/1000mg is generally not recommended during pregnancy, since the Empagliflozin component may affect fetal kidney development, particularly in later stages of pregnancy, and diabetes control in pregnant women is typically managed through alternative treatment options under specialist supervision. It is also generally not advised while breastfeeding. Women who are pregnant, planning to become pregnant, or currently breastfeeding should speak with their doctor before starting or continuing this medication.
Storage Instructions
- Store Jardy-Met 12.5/1000mg tablets at room temperature, ideally below 25°C, away from direct sunlight, heat, and excess humidity.
- Keep the tablets in their original blister packaging until they are needed.
- Store out of the reach of children.
- Do not use tablets past their printed expiry date, and dispose of unused medicine responsibly rather than through household waste.
FAQS
Is 12.5/1000mg the strongest Jardy-Met combination available?
Within this fixed-dose tablet range, it represents the highest strength of both components combined, generally used only once a patient has been shown to tolerate both individually.
Why does this strength require closer monitoring than lower doses?
Because it combines the maximum metformin dose with a higher Empagliflozin dose, your doctor will likely monitor kidney function and hydration status more closely to reduce the risk of complications.
Should this tablet always be taken with food?
Yes, taking it with a meal is strongly recommended, as it significantly reduces the stomach-related side effects associated with the higher metformin dose.
Can I switch directly to 12.5/1000mg from a lower Jardy-Met strength?
No, dose increases should always be made gradually and only under a doctor’s supervision, based on your blood sugar response and tolerance at each step.
Is this combination suitable for patients with reduced kidney function?
It generally requires normal or near-normal kidney function, so your doctor will assess your kidney health before prescribing this particular strength.
Disclaimer
Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.






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