Description
Description
Lomotil (2.5/0.025mg) is a well-known antidiarrheal medicine combining Diphenoxylate Hydrochloride and Atropine Sulfate as its active ingredients. It belongs to a class of medicines that work by slowing down overactive bowel movement, allowing the body more time to absorb water from stool and reduce the frequency of loose motions. This bulk pack contains 500 tablets, each carrying a 2.5mg dose of diphenoxylate combined with 0.025mg of atropine. Lomotil is commonly used as supportive therapy for managing both acute and chronic diarrhea, often prescribed alongside fluid replacement and dietary adjustments to help control symptoms and reduce the risk of dehydration.
Ingredients
Each Lomotil tablet contains Diphenoxylate Hydrochloride 2.5mg and Atropine Sulfate 0.025mg. Diphenoxylate acts on the bowel to slow down its movement, which allows more water to be reabsorbed from the stool, resulting in firmer and less frequent bowel movements. Atropine, included in a very small amount, primarily serves to discourage misuse of the medicine at higher doses, since larger amounts can cause uncomfortable side effects due to its anticholinergic action. Together, these two compounds work in tandem to control diarrhea while limiting the potential for the diphenoxylate component to be misused. The tablet also contains standard inactive excipients used in tablet formulation.
Dosage Form
Lomotil is available as an oral tablet, supplied in a bulk pack of 500 tablets. This larger pack size is often used in clinical or pharmacy settings where the medicine is dispensed to patients based on individual prescriptions and diarrhea severity.
Uses
Lomotil is primarily used as adjunctive therapy in the management of diarrhea, including both acute short-term episodes, such as those related to stomach infections, and chronic diarrhea lasting four weeks or longer, often linked to underlying digestive conditions. It is generally recommended for patients aged thirteen years and above, and is typically used alongside fluid replacement and dietary measures to support recovery and prevent dehydration during a diarrheal illness.
How to Use
Lomotil should be taken exactly as prescribed by a physician, with the standard adult starting dose generally being two tablets taken four times a day, with the dosage gradually reduced as symptoms improve. The tablet should be swallowed with a glass of water and can be taken with or without food. Because Lomotil contains a controlled substance, it should only be used under medical supervision and should never be taken in higher amounts than prescribed. It is not recommended for young children without direct medical guidance.
Side Effects
Common side effects of Lomotil may include dizziness, drowsiness, dry mouth, and nausea. Some individuals may experience headache, restlessness, or abdominal discomfort. Because atropine is present in the formulation, effects such as blurred vision, flushing, or a faster heart rate may also occur, especially if taken in higher than recommended doses. Since diphenoxylate has properties similar to opioids, symptoms of drowsiness or slowed breathing in cases of overdose require urgent medical attention. Any unusual or severe symptoms should be reported to a doctor promptly.
Pregnancy & Breastfeeding
Lomotil should only be used during pregnancy if specifically prescribed by a doctor after careful evaluation of potential risks and benefits. This medicine is known to pass into breast milk, so breastfeeding mothers should consult their doctor before use to determine whether it is appropriate for their situation.
Storage Instructions
Store Lomotil tablets at room temperature, away from direct sunlight, moisture, and excessive heat. Keep the tablets in their original packaging until ready for use, and store them securely, given that this medicine contains a controlled substance. Keep out of reach of children and pets, and do not use tablets beyond their printed expiry date.
FAQS
Is Lomotil safe for children?
It is generally approved for use in individuals aged thirteen and older, and should not be given to young children without direct medical supervision.
Can Lomotil be habit-forming?
While it contains a small amount of a controlled substance, it is not considered addictive at doses recommended for diarrhea, though it should only be used as directed.
Why does Lomotil contain atropine along with diphenoxylate?
Atropine is included in a small amount specifically to discourage misuse of the medicine at higher doses.
Can Lomotil be taken with other medicines?
It may interact with certain medications, so it’s important to inform your doctor about all medicines you are currently taking before starting Lomotil.
Disclaimer
Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.






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