Description

Description

Nise is a non-steroidal anti-inflammatory medicine manufactured by PharmaEvo, containing Nimesulide as its active ingredient. Each pack contains 20 tablets of 100mg strength, used for the short-term relief of pain and inflammation associated with various conditions. Nimesulide works by selectively inhibiting an enzyme involved in the production of prostaglandins, chemical messengers in the body responsible for pain, fever, and inflammation. This selective action is often associated with a somewhat different tolerability profile compared to some older NSAIDs, though it still carries the general risks associated with this class of medicines. Nise is typically used for short durations rather than long-term, ongoing therapy, and should only be taken under medical guidance, particularly given specific safety considerations associated with Nimesulide, including its effects on the liver.

Ingredients

Each tablet of Nise contains Nimesulide 100mg as its active ingredient, a selective COX-2 inhibiting NSAID used for pain and inflammation relief. The tablet also contains standard pharmaceutical excipients required for tablet formation, added in regulator-approved quantities.

Dosage Form

Nise is available as an oral tablet in a 100mg strength, intended for short-term, as-needed use for the management of pain and inflammation.

Uses

Nise is primarily used for the short-term relief of acute pain and inflammation, including conditions such as musculoskeletal pain, sprains, strains, and pain associated with osteoarthritis. It may also be used to help manage postoperative or post-traumatic pain and inflammation, as well as menstrual pain, when recommended by a physician. Nise is generally intended for short courses of treatment rather than continuous long-term use, since prolonged use of Nimesulide is associated with increased risk of certain side effects, particularly involving the liver.

How to Use

Nise should be taken exactly as directed by your doctor or pharmacist, usually with food or after a meal to help reduce the chance of stomach irritation. Tablets should be swallowed whole with a glass of water, and the lowest effective dose should be used for the shortest duration necessary to manage symptoms. Nise should not be taken continuously for more than the period advised by your doctor, and if pain or inflammation persists beyond the recommended treatment window, you should consult your doctor rather than continuing the medicine on your own. This medicine should not be combined with other NSAIDs or pain relievers unless specifically advised by a physician, as this can increase the risk of side effects. If a dose is missed, it should be taken as soon as remembered unless it is close to the time of the next dose, in which case the missed dose should be skipped rather than doubled up.

Side Effects

Nise may cause side effects in some individuals, particularly with higher doses or use beyond the recommended duration. Commonly reported effects include stomach discomfort, heartburn, nausea, or diarrhea. Less commonly, some people may experience dizziness, skin rash, or fluid retention. A key safety consideration with Nimesulide is its potential effect on the liver, and rare but serious cases of liver injury have been reported with its use, which is why treatment duration is generally kept short and why any signs of liver problems, such as yellowing of the skin or eyes, unusual fatigue, dark urine, or persistent nausea, should prompt immediate discontinuation and medical attention. Other NSAID-related risks can include gastrointestinal bleeding, kidney effects, or allergic reactions such as rash, swelling, or difficulty breathing. This list is not exhaustive, and any unusual or persistent symptoms should be reported to your doctor promptly.

Pregnancy & Breastfeeding

Nise is generally not recommended during pregnancy, particularly in the later stages, as NSAIDs including Nimesulide can affect fetal development and increase risks around the time of delivery. It is also generally not recommended during breastfeeding, since it is not fully established how much of the medicine passes into breast milk. Women who are pregnant, planning a pregnancy, or breastfeeding should consult their doctor before using this medicine, so that a safer alternative can be considered if pain relief is needed.

Storage Instructions

Store Nise tablets at room temperature, away from direct sunlight, heat, and moisture. Keep the medicine in its original packaging until ready to use, and keep it out of reach of children and pets. Do not use the tablets beyond their printed expiry date, and dispose of any expired or unused tablets according to local pharmaceutical waste guidelines rather than household trash.

FAQs

Can I take Nise for more than a few days in a row?
Nise is generally intended for short-term use. If your symptoms persist, consult your doctor rather than continuing the medicine beyond the recommended duration.

Is Nise safe for the liver?
Nimesulide carries a specific risk of liver-related side effects, which is why it’s used for short durations and why any signs of liver trouble should be reported to a doctor immediately.

Can I take Nise with other pain relievers?
This should only be done under medical advice, as combining NSAIDs can increase the risk of side effects such as stomach or kidney problems.

What should I do if I miss a dose?
Since Nise is typically used as needed rather than on a strict schedule, simply take your next dose as advised by your doctor if you miss one.

Is Nise suitable for children?
Nimesulide use in children is subject to specific restrictions in many regions, so it should only be given to a child if specifically prescribed by a pediatrician.

Disclaimer

Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.