Description

Description

Lowplat Plus is a prescription-only combination antiplatelet medicine manufactured by PharmaEvo, formulated to help prevent blood clots in patients at higher risk of cardiovascular events. Each pack contains 10 tablets, combining Aspirin 75mg and Clopidogrel 150mg in a single dosage form. Both medicines work by reducing the ability of platelets to stick together and form clots, but through different mechanisms, so combining them can offer more effective clot prevention in specific clinical situations. This particular strength, with a higher 150mg Clopidogrel dose, is typically prescribed for patients who require more intensive antiplatelet coverage, such as during the early period following a cardiac stent procedure or in certain higher-risk acute coronary syndrome cases, based on a physician’s clinical judgment. Lowplat Plus should only be used under close physician supervision, as combining two antiplatelet medicines, particularly at a higher Clopidogrel dose, increases the importance of carefully balancing clot prevention against bleeding risk.

Ingredients

Each tablet of Lowplat Plus (75/150mg) contains Aspirin 75mg, which works by inhibiting an enzyme involved in platelet activation, along with Clopidogrel 150mg (as Clopidogrel Bisulfate or an equivalent salt form), which blocks a separate platelet receptor to further reduce clot formation. The tablet also contains standard pharmaceutical excipients required for tablet formation, added in regulator-approved quantities.

Dosage Form

Lowplat Plus is available as an oral tablet combining Aspirin 75mg with a higher 150mg Clopidogrel strength, intended for once-daily dosing as part of a dual antiplatelet treatment plan, usually for a specific duration determined by a cardiologist or physician based on the clinical scenario.

Uses

Lowplat Plus (75/150mg) is primarily used to reduce the risk of clot-related cardiovascular events in patients who require more intensive combined antiplatelet therapy. It is commonly prescribed following coronary stent placement, particularly in higher-risk cases, where stronger antiplatelet coverage helps prevent clot formation within the stent during the critical healing period, as well as in select patients with acute coronary syndrome or a recent heart attack, when a physician determines that a higher Clopidogrel dose alongside Aspirin offers appropriate protection. The specific duration and appropriateness of this higher-strength combination is determined individually by the treating physician, based on the type of cardiac event, stent type, and the patient’s overall bleeding risk.

How to Use

Lowplat Plus should be taken exactly as prescribed by your doctor, usually as one tablet daily, with or without food. It’s best to take the tablet at the same time each day to maintain consistent blood levels and support its clot-preventing effect. Because this version contains a higher Clopidogrel dose, it should only be used when specifically prescribed at this strength, rather than substituted for a lower-dose version without medical guidance. This medicine should never be stopped abruptly without medical guidance, particularly in patients who have had a stent placed, since early discontinuation of dual antiplatelet therapy can significantly increase the risk of clot formation within the stent. Any planned surgical or dental procedures should be discussed with your doctor well in advance, as this combination may need to be paused temporarily to reduce bleeding risk, though this decision should always be made by your treating physician rather than the patient alone. If a dose is missed, it should be taken as soon as remembered unless it is close to the time of the next dose, in which case the missed dose should be skipped rather than doubled up.

Side Effects

Lowplat Plus may cause side effects in some individuals, and bleeding-related effects may be more pronounced at this higher Clopidogrel strength. Commonly reported effects include easy bruising, nosebleeds, and minor bleeding from cuts that takes longer than usual to stop. Some patients may also experience stomach upset, indigestion, or heartburn, partly related to the Aspirin component. Less commonly, more significant bleeding can occur, such as blood in the stool or urine, coughing up blood, or unusually heavy bruising, which requires prompt medical attention. Rare but serious effects can include stomach ulcers, severe allergic reactions, or a drop in blood cell counts, which may present as unusual fatigue, fever, or signs of infection. This list is not exhaustive, and any unusual bleeding, bruising, or stomach pain should be reported to your doctor without delay.

Pregnancy & Breastfeeding

The use of Lowplat Plus during pregnancy is generally avoided, particularly in later stages, as both Aspirin and Clopidogrel carry potential bleeding-related risks for both mother and baby, especially around the time of delivery, and this risk may be more relevant at the higher Clopidogrel dose. It is also not generally recommended during breastfeeding, since it is not fully established how much of the combination passes into breast milk. Women who are pregnant, planning a pregnancy, or breastfeeding should consult their doctor before starting or continuing this medicine, so that a safer approach can be considered if needed.

Storage Instructions

Store Lowplat Plus tablets at room temperature, away from direct sunlight, heat, and moisture. Keep the medicine in its original packaging until ready to use, and keep it out of reach of children and pets. Do not use the tablets beyond their printed expiry date, and dispose of any expired or unused tablets according to local pharmaceutical waste guidelines rather than household trash.

FAQs

How is this different from the 75/75mg version?
Both contain the same Aspirin dose, but this version contains double the Clopidogrel dose, and is prescribed when a physician determines that more intensive antiplatelet therapy is needed.

Can I switch between the 75/75mg and 75/150mg versions on my own?
No, any change in strength should only be made under a doctor’s supervision, as it directly affects your level of clot protection and bleeding risk.

Can I stop taking Lowplat Plus once I feel better?
No, this medicine should never be stopped without your doctor’s guidance, especially after a stent procedure, since early discontinuation can significantly increase clot risk.

What should I do before surgery or dental work?

Inform your doctor or dentist that you’re taking Lowplat Plus well in advance, as they may need to adjust your treatment temporarily to reduce bleeding risk.

What should I do if I miss a dose?
Take it as soon as you remember, unless it’s near your next scheduled dose, in which case you should skip the missed one rather than doubling up.

Disclaimer

Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.