Description
Description
Empaphage M (5mg/850mg) is a combination oral medication for type 2 diabetes, bringing together Empagliflozin and Metformin to offer a more comprehensive approach to blood sugar management in a single tablet. Each pack contains 14 tablets, providing patients with a convenient two-in-one treatment option rather than managing two separate medications throughout the day. This combination pairs two distinct classes of diabetes medicine, an SGLT2 inhibitor and a biguanide, which work through entirely different mechanisms to help lower blood glucose levels. Beyond its role in blood sugar management, this combination has also been associated with cardiovascular benefits for patients with type 2 diabetes who also have existing heart disease, making it a meaningful option for those managing both conditions simultaneously as part of a broader treatment plan involving diet and exercise.
Ingredients
Each Empaphage M 5mg/850mg tablet contains Empagliflozin at a 5mg strength and Metformin Hydrochloride at an 850mg strength. Empagliflozin belongs to the sodium-glucose co-transporter 2, or SGLT2, inhibitor class of medications, working by reducing the kidneys’ reabsorption of glucose, which allows excess sugar to be removed from the body through urine rather than remaining in the bloodstream. Metformin, from the biguanide class, works differently, lowering the amount of glucose produced by the liver, slowing glucose absorption in the intestines, and improving how effectively the body’s tissues respond to insulin. Together, these two mechanisms address blood sugar regulation from separate but complementary angles.
Dosage Form
Empaphage M 5mg/850mg is supplied as an oral tablet, packaged in a strip format containing 14 tablets, designed for regular use as part of an ongoing diabetes management plan.
Uses
Empaphage M 5mg/850mg is used, along with a proper diet and exercise program, to control high blood sugar levels in adults with type 2 diabetes mellitus. It is also used to help lower the risk of death from heart attack, stroke, or heart failure in adults with type 2 diabetes who also have existing cardiovascular disease. It is not intended for the treatment of type 1 diabetes. By combining Empagliflozin’s glucose-excreting action with Metformin’s liver-glucose-lowering effect, this medication helps patients achieve more consistent blood sugar control, supporting better overall health outcomes and reducing the risk of complications such as kidney damage, eye damage, nerve problems, and cardiovascular events associated with poorly managed diabetes.
How to Use
Empaphage M 5mg/850mg is typically taken twice daily with meals, as directed by your doctor, since taking it with food helps reduce the likelihood of stomach-related side effects associated with the Metformin component. The tablet should be swallowed whole with a glass of water and should not be crushed or chewed. Your doctor may gradually adjust your dose over time, up to a maximum recommended total daily amount, based on how well your blood sugar responds to treatment and how well you tolerate the medication. It’s important to stay well hydrated while on this medication, given the increased urination associated with the Empagliflozin component, and to maintain consistent meal timing to support stable blood sugar control throughout the day.
Side Effects
Common side effects of Empaphage M include nausea, diarrhea, and abdominal discomfort, particularly related to the Metformin component, along with an increased risk of urinary tract infections, genital yeast infections, increased urination, and dehydration linked to the Empagliflozin component. Rarely, too much Metformin can build up in the body and cause a serious condition called lactic acidosis, which is more likely in older adults or those with kidney or liver disease, dehydration, heart failure, or heavy alcohol use, and requires immediate medical attention if symptoms such as unusual tiredness, muscle pain, difficulty breathing, or an irregular heartbeat occur. Serious effects associated with Empagliflozin can include diabetic ketoacidosis and kidney problems, so regular monitoring of kidney function is an important part of ongoing treatment. Alcohol should be limited while taking this medication, as it can increase the risk of lactic acidosis, low blood sugar, and elevated ketone levels.
Pregnancy & Breastfeeding
Empaphage M may be unsafe to use during pregnancy, so it’s important to inform your doctor if you are pregnant or planning to conceive before taking this medication, as your doctor will weigh the potential benefits and risks before determining the best course of treatment. Diabetes management during pregnancy typically requires a different approach, and your doctor can help guide you toward a more suitable alternative if needed. Breastfeeding mothers should also consult their doctor before using this medication, as the safety of its components during breastfeeding requires individual medical assessment.
Storage Instructions
Store Empaphage M 5mg/850mg tablets in a cool, dry place, away from direct sunlight and excess moisture. Keep the tablets in their original packaging until ready for use to help preserve their effectiveness. Store this medication safely out of reach of children and pets, and dispose of any unused or expired tablets responsibly rather than through household waste.
FAQs
Does this medication help with heart health as well as diabetes? Yes, Empaphage M has been associated with a reduced risk of cardiovascular death in patients with type 2 diabetes who also have existing heart disease, in addition to its blood sugar benefits.
Why does this medication increase urination? The Empagliflozin component works by helping the kidneys remove excess glucose through urine, which naturally leads to increased urination as part of its mechanism of action.
Should I drink more water while taking this medication? Yes, staying well hydrated is generally recommended, as this medication can increase fluid loss through more frequent urination.
Can this medication be used for type 1 diabetes? No, Empaphage M is intended specifically for type 2 diabetes and is not suitable for type 1 diabetes or diabetic ketoacidosis.
Will I need regular kidney function tests on this medication? Yes, periodic monitoring of kidney function is typically recommended, since both active ingredients are processed through the kidneys and liver.
Disclaimer
Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.






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