Description
Description
Empoli Plus 5/850mg is a combination tablet manufactured by Sami Pharmaceuticals, bringing together two active ingredients, Empagliflozin and Metformin, in a single dose. This formulation combines two different classes of diabetes medication to help patients achieve more comprehensive blood sugar control than either ingredient might provide on its own. Empagliflozin belongs to a class known as SGLT2 inhibitors, working by reducing the reabsorption of glucose in the kidneys and allowing excess sugar to be removed from the body through urine. Metformin, one of the most established and widely used diabetes medications, works primarily by reducing the amount of glucose produced by the liver and improving the body’s sensitivity to insulin. Together, these two mechanisms address blood sugar from complementary angles, often providing more effective control while simplifying the treatment routine into a single tablet. Each pack of Empoli Plus contains 14 tablets, generally intended for twice-daily use as part of a diabetes management plan established by a physician.
Ingredients
Each Empoli Plus tablet contains two active pharmaceutical ingredients: Empagliflozin at a strength of 5mg and Metformin at a strength of 850mg. The tablet also includes standard pharmaceutical excipients, such as fillers, binding agents, and a film-coating layer, which support the tablet’s stability and ease of swallowing without contributing to its therapeutic effect.
Dosage Form
Empoli Plus is formulated as a film-coated oral tablet, combining 5mg of Empagliflozin with 850mg of Metformin in each unit. The tablets are supplied with a total of 14 units per pack, intended for oral administration only.
Uses
Empoli Plus is primarily used to help manage blood sugar levels in adults with type 2 diabetes who are not adequately controlled on a single diabetes medication, or in those for whom a doctor determines that combination therapy is an appropriate approach. By combining an SGLT2 inhibitor with Metformin, this medicine offers a broader mechanism of blood sugar reduction, helping to lower the long-term risks associated with poorly controlled diabetes, including damage to the eyes, kidneys, nerves, and blood vessels. It may be used as part of a wider treatment plan that also includes dietary and lifestyle adjustments recommended by a healthcare provider.
How to Use
Empoli Plus should be taken exactly as directed by a prescribing physician, typically twice daily with meals, as taking Metformin with food helps reduce the likelihood of stomach upset. The tablet should be swallowed whole with a glass of water and should not be crushed, split, or chewed unless a doctor has specifically advised otherwise. Because this medication includes an SGLT2 inhibitor, maintaining good hydration is important, particularly during illness or hot weather. Doses should not be skipped, and treatment should not be stopped suddenly without consulting a doctor. If a dose is missed, it should be taken as soon as remembered, unless the next dose is nearly due, in which case the missed dose should be skipped rather than doubled.
Side Effects
As a combination medicine, Empoli Plus may cause side effects associated with either or both of its active ingredients. Commonly reported effects include gastrointestinal symptoms such as nausea, diarrhea, and stomach discomfort, which are often linked to the Metformin component and may be more noticeable when starting treatment. Increased urination, urinary tract infections, and genital yeast infections may occur due to the Empagliflozin component. Some patients may also experience a metallic taste or reduced appetite. Less commonly, effects such as dizziness or mild dehydration may develop, particularly if fluid intake is not well maintained. In rare but serious cases, this medication has been associated with a condition called lactic acidosis, related to the Metformin component, as well as diabetic ketoacidosis, related to the Empagliflozin component; both are medical emergencies requiring immediate attention, with symptoms such as unusual muscle pain, difficulty breathing, severe stomach pain, or unusual tiredness warranting urgent medical evaluation. Patients should also be alert to signs of urinary or genital infections and should maintain good hydration throughout treatment.
Pregnancy & Breastfeeding
Empoli Plus is generally not recommended during pregnancy, as the safety of Empagliflozin for the developing baby has not been well established, and alternative treatments, including insulin, are typically preferred during this period. Women who are pregnant, planning to become pregnant, or breastfeeding should inform their doctor, as this medication is also not generally recommended during breastfeeding, and a suitable alternative treatment plan will usually be discussed.
Storage Instructions
Empoli Plus tablets should be stored in a cool, dry place, away from direct sunlight and excessive humidity. It is best to keep the tablets in their original packaging until they are needed and to store them securely out of the reach of children and pets. Tablets should not be used after the expiry date printed on the packaging.
FAQs
Why are two different diabetes medicines combined in one tablet?
Combining Empagliflozin and Metformin allows the two drugs to lower blood sugar through different mechanisms simultaneously, often providing better control than either medicine alone, while simplifying the daily dosing routine.
What is lactic acidosis, and why is it a concern with this medication?
Lactic acidosis is a rare but serious condition related to the Metformin component, where lactic acid builds up in the blood; symptoms such as unusual muscle pain, difficulty breathing, or severe tiredness should be reported to a doctor immediately.
Why is hydration important while taking Empoli Plus?
The Empagliflozin component increases fluid loss through more frequent urination, so staying well hydrated helps reduce the risk of dehydration, particularly during illness or hot weather. Empoli Plus (5/850Mg) price in pakistan.
Can Empoli Plus be paused before certain medical procedures?
Yes, your doctor may advise temporarily stopping this medication before procedures involving contrast dye or surgery, due to the Metformin component, so always inform your healthcare team that you are taking this medicine.
Disclaimer
Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.






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