Description

Description

Lowplat Plus is a prescription-only combination antiplatelet medicine manufactured by PharmaEvo, formulated to help prevent blood clots in patients at higher risk of cardiovascular events. Each pack contains 10 tablets, combining Aspirin 75mg and Clopidogrel 75mg in a single dosage form. Both medicines work by reducing the ability of platelets to stick together and form clots, but through different mechanisms, so combining them can offer more effective clot prevention in specific clinical situations, such as after a cardiac stent procedure or in certain patients with acute coronary syndrome. This dual antiplatelet combination is typically prescribed for a defined treatment period rather than indefinitely, based on the specific cardiac event or procedure a patient has experienced. Lowplat Plus should only be used under close physician supervision, as combining two antiplatelet medicines increases the importance of carefully balancing clot prevention against bleeding risk.

Ingredients

Each tablet of Lowplat Plus contains Aspirin 75mg, which works by inhibiting an enzyme involved in platelet activation, along with Clopidogrel 75mg (as Clopidogrel Bisulfate or an equivalent salt form), which blocks a separate platelet receptor to further reduce clot formation. The tablet also contains standard pharmaceutical excipients required for tablet formation, added in regulator-approved quantities.

Dosage Form

Lowplat Plus is available as an oral tablet combining Aspirin and Clopidogrel in equal 75mg strengths, intended for once-daily dosing as part of a dual antiplatelet treatment plan, usually for a specific duration determined by a cardiologist or physician.

Uses

Lowplat Plus is primarily used to reduce the risk of clot-related cardiovascular events in patients who require combined antiplatelet therapy. It is commonly prescribed following coronary stent placement, where dual antiplatelet therapy helps prevent clot formation within the stent during the critical healing period, as well as in patients with acute coronary syndrome or a recent heart attack, when a physician determines that combination therapy offers greater protection than either medicine alone. The specific duration of treatment with Lowplat Plus is determined individually, based on the type of cardiac event, the type of stent used, and the patient’s overall bleeding risk.

How to Use

Lowplat Plus should be taken exactly as prescribed by your doctor, usually as one tablet daily, with or without food. It’s best to take the tablet at the same time each day to maintain consistent blood levels and support its clot-preventing effect. This medicine should never be stopped abruptly without medical guidance, particularly in patients who have had a stent placed, since early discontinuation of dual antiplatelet therapy can significantly increase the risk of clot formation within the stent. Any planned surgical or dental procedures should be discussed with your doctor well in advance, as this combination may need to be paused temporarily to reduce bleeding risk, though this decision should always be made by your treating physician rather than the patient alone. If a dose is missed, it should be taken as soon as remembered unless it is close to the time of the next dose, in which case the missed dose should be skipped rather than doubled up.

Side Effects

Lowplat Plus may cause side effects in some individuals, with bleeding-related effects being more likely given that it combines two antiplatelet agents. Commonly reported effects include easy bruising, nosebleeds, and minor bleeding from cuts that takes longer than usual to stop. Some patients may also experience stomach upset, indigestion, or heartburn, partly related to the Aspirin component. Less commonly, more significant bleeding can occur, such as blood in the stool or urine, coughing up blood, or unusually heavy bruising, which requires prompt medical attention. Rare but serious effects can include stomach ulcers, severe allergic reactions, or a drop in blood cell counts, which may present as unusual fatigue, fever, or signs of infection. This list is not exhaustive, and any unusual bleeding, bruising, or stomach pain should be reported to your doctor without delay.

Pregnancy & Breastfeeding

The use of Lowplat Plus during pregnancy is generally avoided, particularly in later stages, as both Aspirin and Clopidogrel carry potential bleeding-related risks for both mother and baby, especially around the time of delivery. It is also not generally recommended during breastfeeding, since it is not fully established how much of the combination passes into breast milk. Women who are pregnant, planning a pregnancy, or breastfeeding should consult their doctor before starting or continuing this medicine, so that a safer approach can be considered if needed.

Storage Instructions

Store Lowplat Plus tablets at room temperature, away from direct sunlight, heat, and moisture. Keep the medicine in its original packaging until ready to use, and keep it out of reach of children and pets. Do not use the tablets beyond their printed expiry date, and dispose of any expired or unused tablets according to local pharmaceutical waste guidelines rather than household trash.

FAQs

Why are Aspirin and Clopidogrel combined in this tablet?
Both medicines prevent blood clots through different mechanisms, so combining them offers stronger clot prevention in specific situations, such as after stent placement.

Can I stop taking Lowplat Plus once I feel better?
No, this medicine should never be stopped without your doctor’s guidance, especially after a stent procedure, since early discontinuation can significantly increase clot risk.

How long will I need to take Lowplat Plus?
This depends on your specific condition and treatment plan. Your doctor will determine the appropriate duration based on your cardiac history and stent type, if applicable.

What should I do before surgery or dental work?
Inform your doctor or dentist that you’re taking Lowplat Plus well in advance, as they may need to adjust your treatment temporarily to reduce bleeding risk.

What should I do if I miss a dose?
Take it as soon as you remember, unless it’s near your next scheduled dose, in which case you should skip the missed one rather than doubling up.

Disclaimer

Always use this medicine strictly according to your doctor’s instructions and prescribed dosage.